Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG): a time for a new player in the treatment of respiratory diseases?

D Mokra, J Adamcakova, J Mokry - Antioxidants, 2022 - mdpi.com
(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …

Bioactive molecules of tea as potential inhibitors for RNA-dependent RNA polymerase of SARS-CoV-2

VK Bhardwaj, R Singh, J Sharma, V Rajendran… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease (COVID-19), a worldwide pandemic, is caused by the severe acute
respiratory syndrome-corona virus-2 (SARS-CoV-2). At this moment in time, there are no …

Fighting cytokine storm and immunomodulatory deficiency: By using natural products therapy up to now

MA Mohammed - Frontiers in Pharmacology, 2023 - frontiersin.org
A novel coronavirus strain (COVID-19) caused severe illness and mortality worldwide from
31 December 2019 to 21 March 2023. As of this writing, 761,071,826 million cases have …

Oridonin inhibits SARS‐CoV‐2 by targeting its 3C‐Like protease

B Zhong, W Peng, S Du, B Chen, Y Feng, X Hu… - Small …, 2022 - Wiley Online Library
The current COVID‐19 pandemic, caused by severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2), is an enormous threat to public health. The SARS‐CoV‐2 3C‐like …

Computational Investigations for Identification of Bioactive Molecules from Baccaurea ramiflora and Bergenia ciliata as Inhibitors of SARS-CoV-2 Mpro

JH Zothantluanga, M Abdalla, M Rudrapal… - Polycyclic Aromatic …, 2023 - Taylor & Francis
In this study, a hybrid compound library of 72 phytocompounds from two antiviral medicinal
plants (Baccaurea ramiflora and Bergenia ciliata) was computationally investigated for their …

[HTML][HTML] SARS-CoV-2 neutralizing activity of polyphenols in a special green tea extract preparation

E Kicker, G Tittel, T Schaller, EM Pferschy-Wenzig… - Phytomedicine, 2022 - Elsevier
Background The COVID-19 pandemic will continue to threaten our health care systems in
the next years. In addition to vaccination there is a need for effective tools for prevention and …

Antiviral activity of plant juices and green tea against SARS‐CoV‐2 and influenza virus

M Eggers, P Jungke, V Wolkinger, R Bauer… - Phytotherapy …, 2022 - Wiley Online Library
Respiratory viruses pose a significant threat to global health. They initially infect the naso‐
and oropharyngeal regions, where they amplify, cause symptoms, and may also be …

Bile acids and bile acid activated receptors in the treatment of Covid-19

S Fiorucci, G Urbani, M Biagioli, V Sepe… - Biochemical …, 2023 - Elsevier
Since its first outbreak in 2020, the pandemic caused by the Severe Acute Respiratory
Syndrome-Coronavirus-2 (SARS-CoV-2) has caused the death of almost 7 million people …

Theaflavin 3-gallate inhibits the main protease (Mpro) of SARS-CoV-2 and reduces its count in vitro

M Chauhan, VK Bhardwaj, A Kumar, V Kumar… - Scientific Reports, 2022 - nature.com
The main protease (Mpro) of SARS-CoV-2 has been recognized as an attractive drug target
because of its central role in viral replication. Our previous preliminary molecular docking …