Mosquito-borne West Nile virus (WNV) infection is benign in most individuals but can cause
encephalitis in< 1% of infected individuals. We show that∼ 35% of patients hospitalized for …

Type I interferons (IFNs) have broad and potent antiviral activity. We review the interplay
between type I IFNs and SARS-CoV-2. Human cells infected with SARS-CoV-2 in vitro …

B cells secrete antibodies and mediate the humoral immune response, making them
extremely important in protective immunity against SARS-CoV-2, which caused the …

COVID-19 is associated with neurological complications including stroke, delirium and
encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms …

Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus
disease 2019 (COVID-19) positive cases with an extensive clinical information that were …

Abstract During SARS-CoV-2 infection, the innate immune response can be inhibited or
delayed, and the subsequent persistent viral replication can induce emergency signals that …

Down syndrome (DS), the genetic condition caused by trisomy 21, is characterized by
variable cognitive impairment, immune dysregulation, dysmorphogenesis and increased …

Disclosures: C. Flores reported grants from Instituto de Salud Carlos III, Spanish Ministry of
Science and Innovation, and Cabildo Insular de Tenerife outside the submitted work. J …

SARS-CoV-2 infections display tremendous interindividual variability, ranging from
asymptomatic infections to life-threatening disease. Inborn errors of, and autoantibodies …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of
coronavirus disease 2019 (COVID‐19), has caused millions of deaths in the past two years …