Research status of dendrimer micelles in tumor therapy for drug delivery

X Wang, M Zhang, Y Li, H Cong, B Yu, Y Shen - Small, 2023 - Wiley Online Library
Dendrimers are a family of polymers with highly branched structure, well‐defined
composition, and extensive functional groups, which have attracted great attention in …

A new era in posterior segment ocular drug delivery: Translation of systemic, cell-targeted, dendrimer-based therapies

RM Kannan, I Pitha, KS Parikh - Advanced Drug Delivery Reviews, 2023 - Elsevier
Vision impairment and loss due to posterior segment ocular disorders, including age-related
macular degeneration and diabetic retinopathy, are a rapidly growing cause of disability …

Dendrimers, an emerging opportunity in personalized medicine?

AM Caminade - Journal of personalized medicine, 2022 - mdpi.com
Dendrimers are highly branched macromolecules tailorable at will to fulfil precise
requirements. They have generated a great many expectations and a huge number of …

[HTML][HTML] Properties and bioapplications of amphiphilic janus dendrimers: A Review

A Căta, IMC Ienașcu, MN Ştefănuț, D Roșu, OR Pop - Pharmaceutics, 2023 - mdpi.com
Amphiphilic Janus dendrimers are arrangements containing both hydrophilic and
hydrophobic units, capable of forming ordered aggregates by intermolecular noncovalent …

Solid-phase dendrimer synthesis: a promising approach to transform dendrimer construction

AYT Huang, CL Kao, A Selvaraj, L Peng - Materials Today Chemistry, 2023 - Elsevier
Dendrimers, by virtue of their unique well-defined dendritic structure and multivalent
cooperativity, hold great promise for a wide variety of applications, ranging from healthcare …

Dendrimer–siRNA Conjugates for Targeted Intracellular Delivery in Glioblastoma Animal Models

W Liyanage, T Wu, S Kannan… - ACS Applied Materials & …, 2022 - ACS Publications
Small interfering RNAs (siRNAs) are potent weapons for gene silencing, with an opportunity
to correct defective genes and stop the production of undesirable proteins, with many …

Dendrimers in corneal drug delivery: recent developments and translational opportunities

A Dhull, C Yu, AH Wilmoth, M Chen, A Sharma, S Yiu - Pharmaceutics, 2023 - mdpi.com
Dendrimers are biocompatible organic nanomaterials with unique physicochemical
properties, making them the focus of recent research in drug delivery. The cornea of the …

[HTML][HTML] Dendrimers and derivatives as multifunctional nanotherapeutics for Alzheimer's disease

DA Moreira, SD Santos, V Leiro, AP Pêgo - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. It affects more than 30
million people worldwide and costs over US $1.3 trillion annually. AD is characterized by the …

Dendrimer-based delivery of macromolecules for the treatment of brain tumor

H Choudhury, M Pandey, R Mohgan, JSJ Jong… - Biomaterials …, 2022 - Elsevier
Brain tumor represents the most lethal form of cancer with the highest mortality and morbidity
rates irrespective of age and sex. Advancements in macromolecule-based therapy (such as …

Dendrimer-mediated delivery of DNA and RNA vaccines

LA Kisakova, EK Apartsin, LF Nizolenko, LI Karpenko - Pharmaceutics, 2023 - mdpi.com
DNA and RNA vaccines (nucleic acid-based vaccines) are a promising platform for vaccine
development. The first mRNA vaccines (Moderna and Pfizer/BioNTech) were approved in …