Schizophrenia has been an evolutionary paradox: it has high heritability, but it is associated
with decreased reproductive success. The causal genetic variants underlying schizophrenia …

Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …

As social animals, humans need to live in groups. This contact with conspecifics is essential
for their evolution and survival. Among the recommendations to reduce transmission of the …

BackgroundExploring the neural basis related to different mood states is a critical issue for
understanding the pathophysiology underlying mood switching in bipolar disorder (BD), but …

Humans have been using fire for hundreds of millennia, creating an ancestral expansion
toward the nocturnal niche. The new adaptive challenges faced at night were recurrent …

Cultural innovations, such as tools and other technical articles useful for survival, imply that
creativity is an outcome of evolution. However, the existence of purely ornamental items …

Background Mounting evidence showed that insula contributed to the neurobiological
mechanism of suicidal behaviors in bipolar disorder (BD). However, no studies have …

Bipolar disorder is one of the severe mental diseases. Its high misdiagnosis rate and long-
time delayed diagnosis are related to the fact that the diagnosis procedure is mainly …

While COVID-19 infection and mortality rates are soaring in Western countries, Southeast
Asian countries have successfully avoided the second wave of the SARS-CoV-2 pandemic …

Background: Bipolar disorder is a chronic psychiatric disorder with depression and manic
episodes. It is one of the leading causes of disease-related disability worldwide. Despite the …