C Ponticelli, RJ Glassock - Journal of nephrology, 2019 - Springer
Synthetic immunosuppressive drugs are largely used in immune-related renal diseases and in kidney transplantation. Most of these drugs have a low therapeutic index (the ratio that …
Extracorporeal treatments have been used since the 1970s in the management of systemic lupus erythematosus (SLE). A randomised controlled trial comparing the efficacy of standard …
C Ponticelli, R Escoli, G Moroni - Autoimmunity Reviews, 2018 - Elsevier
Cyclophosphamide is a prodrug that is converted to inactive carboxy-cyclophosphamide, acrolein and phosphoramide mustard, an agent that adds alkyl groups to oxygen and …
C Ponticelli, F Locatelli - Clinical Journal of the American Society …, 2018 - journals.lww.com
Glucocorticoids exert anti-inflammatory and immunosuppressive activities by genomic and nongenomic effects. The classic genomic effects are mediated by cytosolic glucocorticoid …
F Reggiani, V L'Imperio, M Calatroni… - Clin Exp …, 2023 - clinexprheumatol.org
Anti-glomerular basement membrane (anti-GBM) disease is a rare life-threatening small- vessel vasculitis that typically affects the capillaries of kidneys and lungs, with most of …
C Ponticelli, M Calatroni, G Moroni - Autoimmunity Reviews, 2023 - Elsevier
Antiglomerular basement membrane disease (anti-GBM) is a rare life-threatening autoimmune vasculitis that involves small vessels and it is characterized by circulating …
V Binda, G Moroni, P Messa - Journal of nephrology, 2018 - Springer
Systemic vasculitis is a rare but severe group of diseases characterized by inflammation and necrosis of blood vessels. The size of the vessel affected varies among the different forms of …
G Moroni, C Ponticelli - European journal of internal medicine, 2016 - Elsevier
For many years pregnancy has been contraindicated in patients with SLE, particularly when kidney involvement was present. Today, pregnancy is no longer considered impossible in …
K Kaartinen, A Safa, S Kotha, G Ratti, S Meri - Seminars in immunology, 2019 - Elsevier
Glomerulonephritis (GN) refers to a group of renal diseases affecting the glomeruli due to the damage mediated by immunological mechanisms. A large proportion of the disease …