Bacterial resistance to the majority of clinically used β-lactam antibiotics is a global health
threat and, consequently, the driving force for the development of metallo-β-lactamase …

New Delhi metallo-β-lactamase-1 (NDM-1) has emerged as a major global threat to human
health for its rapid rate of dissemination and ability to make pathogenic microbes resistant to …

We use mass spectrometry (MS), under denaturing and non-denaturing solution conditions,
along with ultraviolet photodissociation (UVPD) to characterize structural variations in New …

The development of pathogenic microbial resistance toward antibiotics has become a global
clinical concern. New Delhi metallo-β-lactmase-1 (NDM-1) and its variants have recently …

New Delhi metallo-β-lactmase-1 (NDM-1) catalyzes the hydrolysis of β-lactam antibiotics
and cleaves the β-lactam ring of the molecule, conferring bacterial resistance against these …

New Delhi Metallo β-lactamase-1 (NDM-1) is a member of the Metallo-β-lactamase family,
capable of catalyzing the hydrolysis of all β-lactam antibiotics. The rapid dissemination of …

Background Carbapenemase-producing makes a great contribution to carbapenem
resistance in Gram-negative bacilli. Bla AFM-1 gene was first discovered by us in …

Enolase is a conserved cytoplasmic metalloenzyme existing universally in both eukaryotic
and prokaryotic cells. The enzyme can also locate on the cell surface and bind to …

The increasing antibiotic resistance is a clinical problem worldwide. Numerous Gram-
negative bacteria have already become resistant to the most widely used class of …

The emergence and spread of carbapenemase in Gram-negative pathogens poses an
enormous threat to global public health. New Delhi metallo-β-lactamase-1 (NDM-1) …