The vasopressor octapeptide, angiotensin II (Ang II), exerts homeostatic responses in
cardiovascular tissues, including the heart, blood vessel wall, adrenal cortex and liver (a …

Since the advent of insulin, the improvements in diabetes detection and the therapies to treat
hyperglycemia have reduced the mortality of acute metabolic emergencies, such that today …

Although leukocytes adhere in arteries in various vascular diseases, to date no endogenous
proinflammatory molecule has been identified to initiate leukocyte adhesion in the arterial …

Increased levels of high-sensitivity C-reactive protein (hsCRP) are associated with incident
hypertension as well as cardiovascular events, and angiotensin II is a potent …

Background and Purpose—The spontaneously hypertensive rat (SHR) is vulnerable to brain
ischemia and stress and exhibits a chronically stimulated brain angiotensin II system …

Non-alcoholic fatty liver disease (NAFLD) encompasses pure steatosis through nonalcoholic
steatohepatitis (NASH) and is the most common cause of chronic liver disease in Western …

Angiotensin II (ANG II) has been etiologically linked to vascular disease; however, its role in
the alterations of endothelial function that occur in vascular disorders is not completely …

Endothelial function is largely dictated by its ability to rapidly sense environmental cues and
adapt to these stimuli through changes in vascular tone, inflammation/immune recruitment …

Although vitamin D has been implicated in cardiovascular protection, few studies have
addressed the role of vitamin D receptor (VDR) in atherosclerosis. Here we investigate the …

The role of the renin-angiotensin system (RAS) in angiogenesis is little known. Here, we
show that the angiotensin II (ATII) type 1 (AT1) receptor plays an important role in ischemia …