M Helmstädter, M Simons - Cell and tissue research, 2017 - Springer
Renal diseases are a growing health burden, and innovative models to study their pathomechanisms are greatly needed. Here, we highlight how the fruit fly Drosophila …
J Na, R Cagan - Journal of the American Society of Nephrology, 2013 - journals.lww.com
Drosophila nephrocytes have been an object of study for more than a century. They were named by Bruntz, based on observations of cells around the heart, the central nervous …
A Patir, A Raper, R Fleming… - G3: Genes …, 2023 - academic.oup.com
It is estimated that animals pollinate 87.5% of flowering plants worldwide and that managed honey bees (Apis mellifera) account for 30–50% of this ecosystem service to agriculture. In …
Y Kawasaki, A Matsumoto, T Miyaki, M Kinoshita… - Cell and tissue …, 2019 - Springer
Nephrocytes are similar in structure to podocytes and play a role in the isolation of toxic substances from hemolymph in insects. Drosophila melanogaster nephrocytes have recently …
Drosophila nephrocytes share functional, structural and molecular similarities with human podocytes. It is known that podocytes express the rabphilin 3A (RPH3A)-RAB3A complex …
G Xi, SA Lamba, M Mysh, JS Poulton - Kidney International Reports, 2024 - Elsevier
Introduction Podocyte slit diaphragms are an important component of the glomerular filtration barrier. Podocyte injury frequently includes defects in slit diaphragms, and various …
MM Gass, S Borkowsky, ML Lotz, R Siwek… - Cellular and Molecular …, 2022 - Springer
Drosophila nephrocytes are an emerging model system for mammalian podocytes and proximal tubules as well as for the investigation of kidney diseases. Like podocytes …
QX Fan, SQ Gong, XZ Hong, XM Feng… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: Kidney stone formers have a high rate of stone recurrence after kidney stone removal surgery and there is no effective medication for treatment. Hydroxycitric acid (HCA) …
R Kozyraki, P Verroust, O Cases - Vitamins and Hormones, 2022 - Elsevier
Cubilin (CUBN), the intrinsic factor-vitamin B12 receptor is a large endocytic protein involved in various physiological functions: vitamin B12 uptake in the gut; reabsorption of albumin …