[HTML][HTML] Bone/cartilage targeted hydrogel: Strategies and applications

H Zhang, S Wu, W Chen, Y Hu, Z Geng, J Su - Bioactive materials, 2023 - Elsevier
The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

Nanomedical approaches in the realm of rheumatoid arthritis

AF Radu, SG Bungau - Ageing research reviews, 2023 - Elsevier
Rheumatoid arthritis (RA) is a heterogeneous autoimmune inflammatory disorder defined by
the damage to the bone and cartilage in the synovium, which causes joint impairment and …

[HTML][HTML] Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering

K Chen, Y Li, Y Li, Y Tan, Y Liu, W Pan… - Journal of …, 2023 - Springer
The stimuli-responsive nanofibers prepared by electrospinning have become an ideal
stimuli-responsive material due to their large specific surface area and porosity, which can …

Smart biomaterials for articular cartilage repair and regeneration

Z Gu, J Wang, Y Fu, H Pan, H He… - Advanced Functional …, 2023 - Wiley Online Library
Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

[HTML][HTML] Targeted and responsive biomaterials in osteoarthritis

J Li, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2023 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Inflammation‐Regulated Auto Aggregated Hydrogel Microspheres Via Anchoring Cartilage Deep Matrix for Genes Delivery

L Chen, J Zhang, J Wang, J Lin… - Advanced Functional …, 2023 - Wiley Online Library
The high density structure of cartilage matrix negative charge seriously hinders the
penetration and enrichment of drugs/genes into cartilage tissue. In this study …

[HTML][HTML] A review of advanced multifunctional magnetic nanostructures for cancer diagnosis and therapy integrated into an artificial intelligence approach

B Govindan, MA Sabri, A Hai, F Banat, MA Haija - Pharmaceutics, 2023 - mdpi.com
The new era of nanomedicine offers significant opportunities for cancer diagnostics and
treatment. Magnetic nanoplatforms could be highly effective tools for cancer diagnosis and …

[HTML][HTML] Bone-targeted nanoparticle drug delivery system: an emerging strategy for bone-related disease

Y Chen, X Wu, J Li, Y Jiang, K Xu, J Su - Frontiers in Pharmacology, 2022 - frontiersin.org
Targeted delivery by either systemic or local targeting of therapeutics to the bone is an
attractive treatment for various bone metabolism diseases such as osteoporosis …

[HTML][HTML] Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy

J Wan, Z He, R Peng, X Wu, Z Zhu, J Cui, X Hao… - Journal of …, 2023 - Springer
Osteoarthritis (OA) is a common degenerative joint disease urgently needing effective
treatments. Bone marrow mesenchymal stromal cell-derived exosomes (Exo) are …

Smart stimuli-responsive strategies for titanium implant functionalization in bone regeneration and therapeutics

J Zhang, Y Zhuang, R Sheng, H Tomás… - Materials …, 2024 - pubs.rsc.org
With the increasing and aging of global population, there is a dramatic rise in the demand for
implants or substitutes to rehabilitate bone-related disorders which can considerably …