Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
cystic kidney disease, with patients often having a positive family history that is characterized …

Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a clinical entity defined by
interstitial fibrosis with tubular damage, bland urinalysis and progressive kidney disease …

Background Patients with heterozygous inactivating mutations in DNAJB11 manifest with
cystic but not enlarged kidneys and renal failure in adulthood. Pathogenesis is proposed to …

The human Sec61 complex is a widely distributed and abundant molecular machine. It
resides in the membrane of the endoplasmic reticulum to channel two types of cargo: protein …

Abstract Purpose of Review To provide a comprehensive update on the role of genetic
testing for the evaluation of kidney transplant recipient and living donor candidates. Recent …

The clinical characteristics of autosomal dominant tubulointerstitial kidney disease (ADTKD)
include bland urinary sediment, slowly progressive chronic kidney disease (CKD) with many …

Autosomal dominant tubulointerstitial kidney disease (ADTKD) refers to a group of disorders
with a bland urinary sediment, slowly progressive chronic kidney disease (CKD), and …

Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a rare inherited disorder
characterized by progressive loss of kidney function, nonsignificant urinalysis and …

Chronic kidney disease (CKD) is associated with significant morbidity and mortality
worldwide. In recent years, our understanding of genetic causes of CKD has expanded …

Autosomal dominant tubulointerstitial kidney disease (ADTKD), a rare genetic disorder
characterised by progressive chronic kidney disease, is caused by mutations in different …