Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …

Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …

Background Aberrant expression of circular RNAs contributes to the initiation and
progression of cancers, but the underlying mechanism remains elusive. Methods RNA-seq …

For many decades classical anti-tumor therapies included chemotherapy, radiation and
surgery; however, in the last two decades, following the identification of the genomic drivers …

Glioma is one of the most common and lethal brain tumors. Surgical resection followed by
radiotherapy plus chemotherapy is the current standard of care for patients with glioma. The …

The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery
of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have been largely …

Glioblastoma (GBM) is a grade IV glioma that is the most malignant brain tumor type.
Currently, there are no effective and sufficient therapeutic strategies for its treatment …

Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …

Altering energy metabolism to meet the uncontrolled proliferation and metastasis has
emerged as one of the most significant hallmarks in tumors. However, the detailed molecular …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …