[HTML][HTML] Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum …
J Desantis, A Bazzacco, M Eleuteri, S Tuci… - European Journal of …, 2024 - Elsevier
Abstract To date, Proteolysis Targeting Chimera (PROTAC) technology has been
successfully applied to mediate proteasomal-induced degradation of several …
successfully applied to mediate proteasomal-induced degradation of several …
A Gaussia luciferase reporter assay for the evaluation of coronavirus Nsp5/3CLpro inhibitors
A Vlachou, R Nchioua, K Regensburger, F Kirchhoff… - 2024 - researchsquare.com
Human coronaviruses (hCoVs) infect millions of people every year. Among these, MERS,
SARS-CoV-1, and SARS-CoV-2 caused significant morbidity and mortality and their …
SARS-CoV-1, and SARS-CoV-2 caused significant morbidity and mortality and their …