Non-substance addictive behaviors may involve repetitive rewarding behaviors including
gambling, gaming, sexual activities, internet-use, and buying-shopping. In addictions, there …

Background: Recently, anhedonia has been recognized as an important Research Domain
Criterion (RDoC) by the National Institute of Mental Health. Anhedonia is proposed to play …

Reward Deficiency Syndrome (RDS) encompasses many mental health disorders, including
a wide range of addictions and compulsive and impulsive behaviors. Described as an …

Depression is a frequent non-motor symptom of Parkinson's disease (PD), and may even
precede the onset of motor symptoms of parkinsonism. Beyond its negative influence on …

Background/Aims: This case series presents the novel Genetic Addiction Risk Score
(GARS®) coupled with a customized pro-dopamine regulator matched to polymorphic …

Over years, the regular use of cannabis has substantially increased among young adults, as
indicated by the rise in cannabis use disorder (CUD), with an estimated prevalence of 8. 3 …

Exercise is known to have a myriad of health benefits. There is much to be learned from the
effects of exercise and its potential for prevention, attenuation and treatment of multiple …

Opioid use disorder (OUD) is a mounting public health problem with substantial morbidity
and mortality. Stress involvement in the course of OUD is generally accepted, but little is …

This article describes a unique therapeutic precision intervention, a formulation of
enkephalinase inhibitors, enkephalin, and dopamine-releasing neuronutrients, to induce …

Background: The risk for all addictive drug and non-drug behaviors, especially, in the
unmyelinated Prefrontal Cortex (PFC) of adolescents, is important and complex. Many …