The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

Aging is a complex process influenced by genetics and the environment, leading to
physiological decline and increased susceptibility to diseases. Cognitive decline is a …

The process of cellular senescence is rapidly emerging as a modulator of organismal aging
and disease. Targeting the development and removal of senescent cells is considered a …

As society ages, the number of patients with spinal degenerative diseases (SDD) is
increasing, posing a major socioeconomic problem for patients and their families. SDD …

Human aging, a natural process characterized by structural and physiological changes,
leads to alterations of homeostatic mechanisms, decline of biological functions, and …

Nutrition generally refers to the macro-and micro-nutrients essential for survival, but we do
not simply eat nutrition. Instead, we eat animal-and plant-based foods without always being …

The risk of cardiovascular disease (CVD) is associated with unusual changes in the human
gut microbiota, most commonly coronary atherosclerotic heart disease, hypertension, and …

Osteoporosis and osteoarthritis account for the leading causes of musculoskeletal
dysfunction in older adults. Senescent chondrocyte overburden, inflammation, oxidative …

Aging is one of the world's greatest concerns, requiring urgent, effective, large-scale
interventions to decrease the number of late-life chronic diseases and improve human …

Due to its physiological benefits from in vitro and in vivo points of view, Akkermansia
muciniphila, a common colonizer in the human gut mucous layer, has consistently been …