Inhibitor discovery for emerging drug-target proteins is challenging, especially when target
structure or active molecules are unknown. Here, we experimentally validate the broad utility …

Serial femtosecond crystallography (SFX) revolutionized macromolecular crystallography
over the past decade by enabling the collection of X-ray diffraction data from nano-or …

In macromolecular crystallography, radiation damage limits the amount of data that can be
collected from a single crystal. It is often necessary to merge data sets from multiple crystals; …

Serial crystallography (SX) enables the determination of room-temperature structures with
minimal radiation damage. The photon flux of the pink beam of 1.2% bandwidth (BW) is one …

Serial femtosecond crystallography (SFX) enables the determination of room-temperature
crystal structures of macromolecules with minimized radiation damage and provides time …

Serial crystallography (SX) enables the determination of the structure of macromolecules or
small molecules with minimal radiation damage. In particular, biomolecule structures …

X-ray crystallography is a robust and powerful structural biology technique that provides
high-resolution atomic structures of biomacromolecules. Scientists use this technique to …

Biophysical techniques include various methodologies applied in studying biological
systems at the molecular and cellular level for the drug discovery process. Various methods …

Serial crystallography (SX) is an emerging technique to determine macromolecules at room
temperature. SX with a pump–probe experiment provides the time-resolved dynamics of …

To date, the COVID-19 pandemic has still been infectious around the world, continuously
causing social and economic damage on a global scale. One of the most important …