Supramolecular adhesive hydrogels for tissue engineering applications
Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …
Interleukin-1 and the inflammasome as therapeutic targets in cardiovascular disease
The intracellular sensing protein termed NLRP3 (for NACHT, LRR, and PYD domains-
containing protein 3) forms a macromolecular structure called the NLRP3 inflammasome …
containing protein 3) forms a macromolecular structure called the NLRP3 inflammasome …
Explainable detection of myocardial infarction using deep learning models with Grad-CAM technique on ECG signals
Myocardial infarction (MI) accounts for a high number of deaths globally. In acute MI,
accurate electrocardiography (ECG) is important for timely diagnosis and intervention in the …
accurate electrocardiography (ECG) is important for timely diagnosis and intervention in the …
[HTML][HTML] Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases
Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …
Angiogenesis after acute myocardial infarction
X Wu, MR Reboll, M Korf-Klingebiel… - Cardiovascular …, 2021 - academic.oup.com
Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …
Effects of stress on the development and progression of cardiovascular disease
M Kivimäki, A Steptoe - Nature Reviews Cardiology, 2018 - nature.com
Cardiovascular disease remains the leading cause of disease burden globally, which
underlies the continuing need to identify new complementary targets for prevention. Over the …
underlies the continuing need to identify new complementary targets for prevention. Over the …
Targeting ferroptosis: pathological mechanism and treatment of ischemia‐reperfusion injury
X Li, N Ma, J Xu, Y Zhang, P Yang, X Su… - Oxidative Medicine …, 2021 - Wiley Online Library
Ischemia‐reperfusion (I/R) is a pathological process that occurs in many organs and
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …
The NLRP3 inflammasome in acute myocardial infarction
The heart is extremely sensitive to ischaemic injury. During an acute myocardial infarction
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
LncRNA KLF3-AS1 in human mesenchymal stem cell-derived exosomes ameliorates pyroptosis of cardiomyocytes and myocardial infarction through miR-138-5p …
Q Mao, XL Liang, CL Zhang, YH Pang… - Stem cell research & …, 2019 - Springer
Aim Myocardial infarction (MI) is a severe disease with increased mortality and disability
rates, posing heavy economic burden for society. Exosomes were uncovered to mediate …
rates, posing heavy economic burden for society. Exosomes were uncovered to mediate …
Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury
Myocardial ischemia-reperfusion injury induces a sterile inflammatory response, leading to
further injury that contributes to the final infarct size. Locally released danger-associated …
further injury that contributes to the final infarct size. Locally released danger-associated …