Introduction. Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory
cytokine with upstream regulatory roles in innate and adaptive immunity and is implicated in …

CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow
and their recruitment to sites of injury, as well as affect processes such as cell arrest …

Macrophage migration inhibitory factor (MIF) exerts multiple effects on immune cells, as well
as having functions outside the immune system. MIF can promote inflammation through the …

Strong evidence has been presented linking chronic inflammation to the onset and
pathogenesis of cancer. The multifunctional pro‐inflammatory protein macrophage migration …

Chemokines orchestrate leukocyte recruitment in atherosclerosis and their blockade is a
promising anti-atherosclerotic strategy, but few chemokine-based approaches have …

Highlights•MIF acts cytokine, enzyme, endocrine hormone and chaperon-like molecule.•D-
DT, a member of the MIF family, exerts non-redundant effects from MIF.•MIF and D-DT are up …

Introduction: CD74, also known as the invariant chain, participates in several key processes
of the immune system, including antigen presentation, B-cell differentiation and inflammatory …

Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with a pleiotropic
spectrum of biological functions implicated in the pathogenesis of cancer and inflammatory …

Macrophage migration inhibitory factor (MIF) has been defined as an important chemokine-
like function (CLF) chemokine with an essential role in monocyte recruitment and arrest …

Introduction: Macrophage migration inhibitory factor (MIF) has emerged as a promising drug
target in diseases including sepsis, rheumatoid arthritis, and cancer. MIF has multiple …