Staphylococcus aureus pneumonia in the community

H He, RG Wunderink - Seminars in respiratory and critical care …, 2020 - thieme-connect.com
Staphylococcus aureus is an emergent etiology of community-acquired pneumonia (CAP)
over the past 2 decades, with severe community-acquired pneumonia (SCAP) caused by …

Viral respiratory pathogens and lung injury

N Clementi, S Ghosh, M De Santis… - Clinical microbiology …, 2021 - Am Soc Microbiol
Several viruses target the human respiratory tract, causing different clinical manifestations
spanning from mild upper airway involvement to life-threatening acute respiratory distress …

Accuracy of biomarkers for the diagnosis of adult community‐acquired pneumonia: a meta‐analysis

MH Ebell, M Bentivegna, X Cai… - Academic …, 2020 - Wiley Online Library
Background Biomarkers such as C‐reactive protein (CRP) and procalcitonin may help
distinguish community‐acquired pneumonia (CAP) from other causes of lower respiratory …

Systematic review of clinical practice guidelines on the management of community acquired pneumonia in children

E Chee, K Huang, S Haggie, PN Britton - Paediatric Respiratory Reviews, 2022 - Elsevier
Childhood community acquired pneumonia (CAP) is the leading cause of mortality in
children under 5 years worldwide. Clinical practice guidelines (CPGs) may be limited by …

Serum ferritin as a predictor of outcomes in hospitalized patients with Covid-19 pneumonia

DA Shakaroun, MH Lazar… - Journal of intensive …, 2023 - journals.sagepub.com
Purpose: Elevated ferritin levels are associated with poor outcomes in Covid-19 patients.
Optimal timing of ferritin assessment and the merit of longitudinal values remains unclear …

Enhanced Detection of community-acquired pneumonia pathogens with the BioFire® Pneumonia FilmArray® Panel

DN Gilbert, JE Leggett, L Wang, S Ferdosian… - … and infectious disease, 2021 - Elsevier
Background Although most observational studies identify viral or bacterial pathogens in 50%
or less of patients hospitalized with community-acquired pneumonia (CAP), we previously …

BioFire® FilmArray® Pneumonia Panel for Severe Lower Respiratory Tract Infections: Subgroup Analysis of a Randomized Clinical Trial

E Kyriazopoulou, A Karageorgos… - Infectious Diseases and …, 2021 - Springer
Introduction The epidemiology of severe lower respiratory tract infections (LRTI) is constantly
changing. We aimed to describe it using the BioFire® FilmArray® Pneumonia plus (PN plus) …

[HTML][HTML] Distinguishing bacterial versus non-bacterial causes of febrile illness–a systematic review of host biomarkers

BL Fernandez-Carballo, C Escadafal, E MacLean… - Journal of Infection, 2021 - Elsevier
Abstract Background Acute febrile illnesses (AFIs) represent a major disease burden
globally; however, the paucity of reliable, rapid point-of-care testing makes their diagnosis …

Prospective validation of a rapid host gene expression test to discriminate bacterial from viral respiratory infection

ER Ko, R Henao, K Frankey, EA Petzold… - JAMA network …, 2022 - jamanetwork.com
Importance Bacterial and viral causes of acute respiratory illness (ARI) are difficult to
clinically distinguish, resulting in the inappropriate use of antibacterial therapy. The use of a …

Benchmarking transcriptional host response signatures for infection diagnosis

DG Chawla, A Cappuccio, A Tamminga, SC Sealfon… - Cell Systems, 2022 - cell.com
Identification of host transcriptional response signatures has emerged as a new paradigm
for infection diagnosis. For clinical applications, signatures must robustly detect the …