Host-based diagnostics for acute respiratory infections

MH Ross, BL Zick, EL Tsalik - Clinical therapeutics, 2019 - Elsevier
Purpose The inappropriate use of antimicrobials, especially in acute respiratory infections
(ARIs), is largely driven by difficulty distinguishing bacterial, viral, and noninfectious …

Antibiotic stewardship in the era of precision medicine

RR Watkins - JAC-antimicrobial resistance, 2022 - academic.oup.com
Antimicrobial resistance (AMR) continues to spread at an alarming rate worldwide. Novel
approaches are needed to mitigate its deleterious impact on antibiotic efficacy. Antibiotic …

Neglected variables in the interpretation of serum procalcitonin levels in patients with septic shock

DN Gilbert - The Journal of infectious diseases, 2020 - academic.oup.com
The interpretation of serum procalcitonin (PCT) levels in septic patients is facilitated by
reviewing the known stimuli that activate the PCT family of genes. Herein we describe 7 …

Control de antibióticos en tiempos de COVID-19

C Chiara-Chilet, M Saavedra-Velasco - Revista de la Facultad de …, 2020 - scielo.org.pe
En lo que va de la pandemia del COVID-19, se observa un incremento en el uso de
antibióticos, siendo probablemente una de las principales razones la incertidumbre que …

Impact of procalcitonin guidance with an educational program on management of adults hospitalized with pneumonia

TL Walsh, BE DiSilvio, C Hammer, M Beg… - The American Journal of …, 2018 - Elsevier
Background Community-acquired pneumonia and healthcare-associated pneumonia are
often treated with prolonged antibiotic therapy. Procalcitonin (PCT) has effectively and safely …

Peripartum Sepsis

AJ Vaught - Current Obstetrics and Gynecology Reports, 2023 - Springer
Abstract Purpose of Review Maternal sepsis is a leading cause of maternal mortality. The
purpose of this review is to go in standard and nuanced care in its treatment and diagnosis …

Guía de práctica clínica para el manejo de la neumonía adquirida en la comunidad

JA Cortés, SI Cuervo-Maldonado… - Revista de la …, 2022 - dialnet.unirioja.es
La neumonía sigue siendo una de las principales causas de consulta y de hospitalización a
la que, además de su un alto impacto en términos de morbilidad y mortalidad, se suma la …

Average weighted accuracy: pragmatic analysis for a rapid diagnostics in categorizing acute lung infections (RADICAL) study

Y Liu, EL Tsalik, Y Jiang, ER Ko… - Clinical Infectious …, 2020 - academic.oup.com
Patient management relies on diagnostic information to identify appropriate treatment.
Standard evaluations of diagnostic tests consist of estimating sensitivity, specificity …

A high α1-antitrypsin/interleukin-10 ratio predicts bacterial pneumonia in adults with community-acquired pneumonia: a prospective cohort study

T Miyazaki, K Fukushima, K Hashiguchi, S Ide… - Pneumonia, 2023 - Springer
Background Current microbiological tests fail to identify the causative microorganism in
more than half of all pneumonia cases. We explored biomarkers that could be used for …

[HTML][HTML] Этиотропная терапия COVID-19: критический анализ и перспективы

НВ Белобородова, ЕВ Зуев, МН Замятин… - Общая …, 2020 - cyberleninka.ru
Эпидемия COVID-19, начавшаяся в декабре 2019 года в Китае, за несколько месяцев
распространилась на все страны мира, приняв характер пандемии, число заболевших …