L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …
LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …
MA Curtis, PI Diaz, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
The last decade has witnessed unparalleled advances in our understanding of the complexity of the oral microbiome and the compositional changes that occur in subgingival …
Recent advances indicate that periodontitis is driven by reciprocally reinforced interactions between a dysbiotic microbiome and dysregulated inflammation. Inflammation is not only a …
Functional profiles of microbial communities are typically generated using comprehensive metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as dental caries and periodontitis, two of the most prevalent microbially induced disorders …
E Read, MA Curtis, JF Neves - Nature Reviews Gastroenterology & …, 2021 - nature.com
Over the past two decades, the importance of the microbiota in health and disease has become evident. Pathological changes to the oral bacterial microbiota, such as those …
The primary etiological agent for the initiation and progression of periodontal disease is the dental plaque biofilm which is an organized aggregation of microorganisms residing within a …
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological balance via both inter‐microbial and host‐microbial interactions that promote their own and …