Off-label prescribing of antipsychotics in adults, children and elderly individuals: a systematic review of recent prescription trends

L Carton, O Cottencin… - Current …, 2015 - ingentaconnect.com
Introduction: New antipsychotics continuously arrive on the market, which thereby influences
the approved and off-label prescribing (OLP) schemes. We aimed to identify the recent …

Multimorbidity and patient safety incidents in primary care: a systematic review and meta-analysis

M Panagioti, J Stokes, A Esmail, P Coventry… - PloS one, 2015 - journals.plos.org
Background Multimorbidity is increasingly prevalent and represents a major challenge in
primary care. Patients with multimorbidity are potentially more likely to experience safety …

Association of off-label drug use and adverse drug events in an adult population

T Eguale, DL Buckeridge, A Verma… - JAMA internal …, 2016 - jamanetwork.com
Importance Off-label use of prescription drugs has been identified as an important
contributor to preventable adverse drug events (ADEs) in children. Despite concerns …

Off-label indications for antidepressants in primary care: descriptive study of prescriptions from an indication based electronic prescribing system

J Wong, A Motulsky, M Abrahamowicz, T Eguale… - bmj, 2017 - bmj.com
Objective To examine off-label indications for antidepressants in primary care and determine
the level of scientific support for off-label prescribing. Design Descriptive study of …

Institutional corruption of pharmaceuticals and the myth of safe and effective drugs

DW Light, J Lexchin, JJ Darrow - Journal of Law, Medicine & Ethics, 2013 - cambridge.org
Institutional corruption is a normative concept of growing importance that embodies the
systemic dependencies and informal practices that distort an institution's societal mission …

[HTML][HTML] Lower-dose prescribing: minimizing “side effects” of pharmaceuticals on society and the environment

CG Daughton, IS Ruhoy - Science of the total Environment, 2013 - Elsevier
The prescribed use of pharmaceuticals can result in unintended, unwelcomed, and
potentially adverse consequences for the environment and for those not initially targeted for …

[HTML][HTML] Off-label uses of selective serotonin reuptake inhibitors (SSRIs)

TB Jannini, GD Lorenzo, E Bianciardi… - Current …, 2022 - ncbi.nlm.nih.gov
Psychiatric drugs have primacy for off-label prescribing. Among those, selective serotonin
reuptake inhibitors (SSRIs) are highly versatile and, therefore, widely prescribed. Moreover …

Weight gain and glucose dysregulation with second-generation antipsychotics and antidepressants: a review for primary care physicians

M Hasnain, WVR Vieweg, B Hollett - Postgraduate medicine, 2012 - Taylor & Francis
Second–generation antipsychotics (SGAPs) and second–generation antidepressants
(SGADs) have multiple US Food and Drug Administration–approved indications and are …

Patterns and predictors of off-label prescription of psychiatric drugs

A Vijay, JE Becker, JS Ross - PLoS One, 2018 - journals.plos.org
Off-label prescribing of psychiatric drugs is common, despite lacking strong scientific
evidence of efficacy and potentially increasing risk for adverse events. The goal of this study …

Physicians' reasons not to discontinue long‐term used off‐label antipsychotic drugs in people with intellectual disability

GM De Kuijper, PJ Hoekstra - Journal of Intellectual Disability …, 2017 - Wiley Online Library
Background People with intellectual disability (ID) frequently use antipsychotic drugs on an
off‐label base, often for many years. Physicians' decisions to discontinue these drugs not …