Acute brain failure: pathophysiology, diagnosis, management, and sequelae of delirium

JR Maldonado - Critical care clinics, 2017 - criticalcare.theclinics.com
Delirium is the most common neuropsychiatric syndrome found in the acute care setting,
with a prevalence ranging from 10% in general medicine to 85% in advanced cancer and …

[HTML][HTML] Efficacy of perioperative dexmedetomidine on postoperative delirium: systematic review and meta-analysis with trial sequential analysis of randomised …

X Duan, M Coburn, R Rossaint, RD Sanders… - British journal of …, 2018 - Elsevier
Background The influence of dexmedetomidine on postoperative delirium (POD) in adult
surgical patients remains controversial. We aimed to analyse whether dexmedetomidine use …

Dexmedetomidine for reduction of atrial fibrillation and delirium after cardiac surgery (DECADE): a randomised placebo-controlled trial

A Turan, A Duncan, S Leung, N Karimi, J Fang, G Mao… - The Lancet, 2020 - thelancet.com
Background Atrial fibrillation and delirium are common consequences of cardiac surgery.
Dexmedetomidine has unique properties as sedative agent and might reduce the risk of …

Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial

G Djaiani, N Silverton, L Fedorko, J Carroll, R Styra… - …, 2016 - pubs.asahq.org
Background Postoperative delirium (POD) is a serious complication after cardiac surgery.
Use of dexmedetomidine to prevent delirium is controversial. The authors hypothesized that …

Serotonin—Its synthesis and roles in the healthy and the critically ill

M Kanova, P Kohout - International journal of molecular sciences, 2021 - mdpi.com
Serotonin (5-hydroxytryptamine, 5-HT) plays two important roles in humans—one central
and the other peripheral—depending on the location of the 5-HT pools of on either side of …

[HTML][HTML] Postoperative delirium

ST Oh, JY Park - Korean journal of anesthesiology, 2019 - synapse.koreamed.org
Delirium can be defined as an 'acute brain dysfunction.'Compared to dementia, which is a
disease that deteriorates the brain function chronically, delirium shows very similar …

[HTML][HTML] Recent advances in preventing and managing postoperative delirium

P Vlisides, M Avidan - F1000Research, 2019 - ncbi.nlm.nih.gov
Postoperative delirium is a common and harrowing complication in older surgical patients.
Those with cognitive impairment or dementia are at especially high risk for developing …

The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta‐analysis with trial sequential analysis

KT Ng, CJ Shubash, JS Chong - Anaesthesia, 2019 - Wiley Online Library
Delirium is common in intensive care patients. Dexmedetomidine is increasingly used for
sedation in this setting, but its effect on delirium remains unclear. The primary aim of this …

Effect of dexmedetomidine on postoperative cognitive dysfunction and inflammation in patients after general anaesthesia: A PRISMA-compliant systematic review and …

W Yang, LS Kong, XX Zhu, RX Wang, Y Liu, LR Chen - Medicine, 2019 - journals.lww.com
Background: Neuroprotective effects of dexmedetomidine are reported in preclinical and
clinical studies but evidence regarding the postoperative neurocognitive function is still …

Mental health of quarantine and isolation

D Huremović - Psychiatry of pandemics: A mental health response to …, 2019 - Springer
Isolating exposed individuals from the unexposed ones is a crucial measure in breaking up
a chain of infection. All forms of separation and isolation, however, tend to impose an …