Molecular pathways of major depressive disorder converge on the synapse

GR Fries, VA Saldana, J Finnstein, T Rein - Molecular psychiatry, 2023 - nature.com
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Neuroinflammation and depression: A review

R Troubat, P Barone, S Leman… - European journal of …, 2021 - Wiley Online Library
Some recent clinical and preclinical evidence suggests that neuroinflammation is a key
factor that interacts with the three neurobiological correlates of major depressive disorder …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

The self in context: brain systems linking mental and physical health

L Koban, PJ Gianaros, H Kober… - Nature Reviews …, 2021 - nature.com
Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

[HTML][HTML] Child and adolescent depression: A review of theories, evaluation instruments, prevention programs, and treatments

E Bernaras, J Jaureguizar, M Garaigordobil - Frontiers in psychology, 2019 - frontiersin.org
Depression is the principal cause of illness and disability in the world. Studies charting the
prevalence of depression among children and adolescents report high percentages of …

[HTML][HTML] Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial …

P Tian, KJ O'Riordan, Y Lee, G Wang, J Zhao… - Neurobiology of …, 2020 - Elsevier
Background Accumulating evidence points to an association between gut microbial
abnormalities and depression disorder. The microbiota-gut-brain axis is an emerging target …

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

L Hoyles, T Snelling, UK Umlai, JK Nicholson… - Microbiome, 2018 - Springer
Background Gut microbiota composition and function are symbiotically linked with host
health and altered in metabolic, inflammatory and neurodegenerative disorders. Three …

Biological, psychological, and social determinants of depression: a review of recent literature

O Remes, JF Mendes, P Templeton - Brain sciences, 2021 - mdpi.com
Depression is one of the leading causes of disability, and, if left unmanaged, it can increase
the risk for suicide. The evidence base on the determinants of depression is fragmented …

[HTML][HTML] The HPA axis dysregulation in severe mental illness: Can we shift the blame to gut microbiota?

B Misiak, I Łoniewski, W Marlicz, D Frydecka… - Progress in Neuro …, 2020 - Elsevier
Accumulating evidence indicates that patients with severe mental disorders, including major
depression, bipolar disorder and schizophrenia present with various alterations of the gut …