[HTML][HTML] The anti-inflammatory role of omega-3 polyunsaturated fatty acids metabolites in pre-clinical models of psychiatric, neurodegenerative, and neurological …

J Giacobbe, B Benoiton, P Zunszain… - Frontiers in …, 2020 - frontiersin.org
Inflammation has been identified as one of the main pathophysiological mechanisms
underlying neuropsychiatric and neurodegenerative disorders. Despite the role of …

The role of the microbiome in the neurobiology of social behaviour

A Sarkar, S Harty, KVA Johnson, AH Moeller… - Biological …, 2020 - Wiley Online Library
Microbes colonise all multicellular life, and the gut microbiome has been shown to influence
a range of host physiological and behavioural phenotypes. One of the most intriguing and …

Targeting PDK2 rescues stress-induced impaired brain energy metabolism

C Wang, C Cui, P Xu, L Zhu, H Xue, B Chen… - Molecular …, 2023 - nature.com
Depression is a mental illness frequently accompanied by disordered energy metabolism. A
dysregulated hypothalamus pituitary adrenal axis response with aberrant glucocorticoids …

Molecular links between endocrine, nervous and immune system during chronic stress

R Zefferino, S Di Gioia, M Conese - Brain and behavior, 2021 - Wiley Online Library
Introduction The stress response is different in various individuals, however, the
mechanisms that could explain these distinct effects are not well known and the molecular …

Molecular aspects of depression: a review from neurobiology to treatment

GRV Boas, RB de Lacerda, MM Paes, P Gubert… - European journal of …, 2019 - Elsevier
Major depressive disorder (MDD), also known as unipolar depression, is one of the leading
causes of disability and disease worldwide. The signs and symptoms are low self‑esteem …

Stress and coping in women with breast cancer: unravelling the mechanisms to improve resilience

M Borgi, B Collacchi, E Ortona, F Cirulli - Neuroscience & Biobehavioral …, 2020 - Elsevier
Breast cancer diagnosis, surgery, adjuvant therapies and survivorship can all be extremely
stressful. In women, concerns about body image are common as a result of the disease and …

[HTML][HTML] Whole-blood expression of inflammasome-and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and …

A Cattaneo, C Ferrari, L Turner, N Mariani… - Translational …, 2020 - nature.com
The mRNA expression signatures associated with the 'pro-inflammatory'phenotype of
depression, and the differential signatures associated with depression subtypes and the …

Biomarkers of pathological dissociation: a systematic review

MI Roydeva, AATS Reinders - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Pathological dissociation is a severe, debilitating and transdiagnostic psychiatric symptom.
This review identifies biomarkers of pathological dissociation in a transdiagnostic manner to …

Physical exercise and neuroinflammation in major depressive disorder

ZM Ignácio, RS da Silva, ME Plissari, J Quevedo… - Molecular …, 2019 - Springer
Major depressive disorder (MDD) is a prevalent psychiatric disorder associated with varied
prognosis, chronic course, and duration of illness with reduced quality of life. One factor that …

[HTML][HTML] Treatment-resistant depression revisited: a glimmer of hope

A Halaris, E Sohl, EA Whitham - Journal of personalized medicine, 2021 - mdpi.com
Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder worldwide. It
causes individual suffering, loss of productivity, increased health care costs and high suicide …