Tight connections between the brain and heart have attracted a considerable amount of
attention. This review focuses on the anatomical (extrinsic cardiac autonomic nervous …

The purpose of this study was to estimate the pharmacological effect of geniposide (GEN) on
depression, caused by chronic unpredictable mild stress (CUMS), and explore its potential …

Despite the important advances in the understanding of the pathophysiology of MDD, a
large proportion of depressed patients do not respond well to currently available …

There is evidence that plasma cortisol concentration can be either increased or decreased
in patients with depression and related anxiety and stress-related disorders; the exact …

Five new aromatic compounds, designed as lucidumins AD (1–4) and lucidimine E (9),
along with seven known aromatic compounds (5–8, 10–12) were isolated from Ganoderma …

The development of resistance to glucocorticoids (GCs) in therapeutic regimens poses a
major threat. Generally, GC resistance is congenital or acquired over time as a result of …

Background Converging and accumulating evidence for the cross‐communication among
the nervous, immune, and endocrine systems, a field of study known as …

The decrease of microglia in the hippocampus is a novel mechanism for depression onset.
Reversal of this decrease can ameliorate stress-induced depression-like behaviors in …

Anecdotal evidence has long suggested that patients with lower urinary tract symptoms
(LUTS) develop mood disorders, such as depression and anxiety, at a higher rate than the …

Background: Major depressive disorder (MDD) is a complex psychiatric condition with
different subtypes and etiologies. Exposure to adverse childhood experiences (ACE) is an …