[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …

[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …

[HTML][HTML] Virology, epidemiology, pathogenesis, and control of COVID-19

Y Jin, H Yang, W Ji, W Wu, S Chen, W Zhang, G Duan - Viruses, 2020 - mdpi.com
The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
disease (COVID-19) in China has been brought to global attention and declared a pandemic …

[HTML][HTML] Understanding SARS-CoV-2-mediated inflammatory responses: from mechanisms to potential therapeutic tools

Y Fu, Y Cheng, Y Wu - Virologica Sinica, 2020 - Springer
Currently there is no effective antiviral therapy for SARS-CoV-2 infection, which frequently
leads to fatal inflammatory responses and acute lung injury. Here, we discuss the various …

COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
Currently, humans are immersed in a pandemic caused by the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which threatens public health …

[HTML][HTML] Impact of COVID-19 in the mental health in elderly: psychological and biological updates

RE Grolli, MED Mingoti, AG Bertollo, AR Luzardo… - Molecular …, 2021 - Springer
Since December 2019, the world has been experiencing the challenge of facing coronavirus
disease-19 (COVID-19), a severe infectious disease caused by the new coronavirus, SARS …

[HTML][HTML] ACE2/ADAM17/TMPRSS2 interplay may be the main risk factor for COVID-19

D Zipeto, JF Palmeira, GA Argañaraz… - Frontiers in …, 2020 - frontiersin.org
The Coronavirus Disease 2019 (COVID-19) has already caused hundreds of thousands of
deaths worldwide in a few months. Cardiovascular disease, hypertension, diabetes and …

Endothelial dysfunction and thrombosis in patients with COVID-19—brief report

S Nagashima, MC Mendes… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Alveolar-capillary endothelial cells can be activated by severe acute respiratory
syndrome coronavirus 2 infection leading to cytokine release. This could trigger endothelial …