Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Neuroinflammation is the fundamental immune response against multiple factors in the
central nervous system and is characterized by the production of inflammatory mediators …

Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Alzheimer's disease (AD), the most common type of senile dementia, includes the complex
pathogenesis of abnormal deposition of amyloid beta-protein (Aβ), phosphorylated tau (p …

Parkinson's Disease (PD) is the second most common neurodegenerative disorder seen,
especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance …

Although Alzheimer's disease is the most pervasive neurodegenerative disorder, the
mechanism underlying its development is still not precisely understood. Available data …

Parkinson's disease (PD) is a slowly progressive neurodegenerative disease characterized
by α-synuclein aggregation and dopaminergic neuronal death. Recent evidence suggests …

Despite potent suppression of HIV-1 viral replication in the central nervous system (CNS) by
antiretroviral therapy (ART), between 15% and 60% of HIV-1-infected patients receiving ART …

Multiple sclerosis (MS) is a chronic, inflammatory, and degenerative disease of the central
nervous system (CNS). Inflammation is observed in all stages of MS, both within and around …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by protein
aggregation in the brain. Recent studies have revealed the critical role of microglia in AD …