[HTML][HTML] Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management
EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
[HTML][HTML] Immunomodulatory mechanisms of mesenchymal stem cells and their potential clinical applications
Y Huang, Q Wu, PKH Tam - International Journal of Molecular Sciences, 2022 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity of self-renewal,
homing, and low immunogenicity. These distinct biological characteristics have already …
homing, and low immunogenicity. These distinct biological characteristics have already …
[HTML][HTML] Nebulized exosomes derived from allogenic adipose tissue mesenchymal stromal cells in patients with severe COVID-19: a pilot study
YG Zhu, M Shi, A Monsel, C Dai, X Dong… - Stem cell research & …, 2022 - Springer
Background Existing clinical studies supported the potential efficacy of mesenchymal
stromal cells as well as derived exosomes in the treatment of COVID-19. We aimed to …
stromal cells as well as derived exosomes in the treatment of COVID-19. We aimed to …
[HTML][HTML] Spotlight on therapeutic efficiency of mesenchymal stem cells in viral infections with a focus on COVID-19
S Yasamineh, HG Kalajahi, P Yasamineh… - Stem Cell Research & …, 2022 - Springer
The SARS-COV-2 virus has infected the world at a very high rate by causing COVID-19
disease. Nearly 507 million individuals have been infected with this virus, with …
disease. Nearly 507 million individuals have been infected with this virus, with …
[HTML][HTML] Systematic review and meta-analysis of cell therapy for COVID-19: global clinical trial landscape, published safety/efficacy outcomes, cell product …
PS Couto, N Al-Arawe, IS Filgueiras… - Frontiers in …, 2023 - frontiersin.org
During the pandemic of severe respiratory distress syndrome coronavirus 2 (SARS-CoV2),
many novel therapeutic modalities to treat Coronavirus 2019 induced disease (COVID-19) …
many novel therapeutic modalities to treat Coronavirus 2019 induced disease (COVID-19) …
[HTML][HTML] Bone marrow-derived mesenchymal stromal cell therapy in severe COVID-19: preliminary results of a phase I/II clinical trial
C Grégoire, N Layios, B Lambermont… - Frontiers in …, 2022 - frontiersin.org
Background Treatment of acute respiratory distress syndrome (ARDS) associated with
COronaVIrus Disease-2019 (COVID-19) currently relies on dexamethasone and supportive …
COronaVIrus Disease-2019 (COVID-19) currently relies on dexamethasone and supportive …
[HTML][HTML] The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials
F Wang, Y Li, B Wang, J Li, Z Peng - Critical Care, 2023 - Springer
Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human
trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 …
trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 …
[HTML][HTML] Key role of mesenchymal stromal cell interaction with macrophages in promoting repair of lung injury
Lung macrophages (Mφs) are essential for pulmonary innate immunity and host defense
due to their dynamic polarization and phenotype shifts. Mesenchymal stromal cells (MSCs) …
due to their dynamic polarization and phenotype shifts. Mesenchymal stromal cells (MSCs) …
Repair of acute respiratory distress syndrome in COVID-19 by stromal cells (REALIST-COVID Trial): a multicenter, randomized, controlled clinical trial
EA Gorman, J Rynne, HJ Gardiner… - American journal of …, 2023 - atsjournals.org
Rationale: Mesenchymal stromal cells (MSCs) may modulate inflammation, promoting repair
in coronavirus disease (COVID-19)–related acute respiratory distress syndrome (ARDS) …
in coronavirus disease (COVID-19)–related acute respiratory distress syndrome (ARDS) …
[HTML][HTML] Efficacy and safety of human umbilical cord-derived mesenchymal stem cells for COVID-19 pneumonia: a meta-analysis of randomized controlled trials
Q Liu, F Ma, Y Zhong, G Wang, L Hu, Y Zhang… - Stem Cell Research & …, 2023 - Springer
Background Elevated levels of inflammatory factors are associated with poor prognosis in
coronavirus disease-19 (COVID-19). However, mesenchymal stem cells (MSCs) have …
coronavirus disease-19 (COVID-19). However, mesenchymal stem cells (MSCs) have …