Efficacy of umbilical cord mesenchymal stromal cells for COVID-19: A systematic review and meta-analysis

C Yang, R Chen, Q Zhu, S Han, M Kuang - Frontiers in Immunology, 2022 - frontiersin.org
Objectives A major challenge for COVID-19 therapy is dysregulated immune response
associated with the disease. Umbilical cord mesenchymal stromal cells (UC-MSCs) may be …

Mesenchymal stromal cells as treatment for acute respiratory distress syndrome. Case Reports following hematopoietic cell transplantation and a review

B Sadeghi, O Ringdén, B Gustafsson… - Frontiers in …, 2022 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is a life-threatening lung disease. It may occur
during the pancytopenia phase following allogeneic hematopoietic cell transplantation …

[HTML][HTML] An international society for cell and gene therapy mesenchymal stromal cells committee editorial on overcoming limitations in clinical trials of mesenchymal …

DJ Weiss, A Filiano, J Galipeau, M Khoury… - …, 2022 - ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19)-related respiratory failure is a significant cause of
morbidity, mortality and health care utilization. Further, long-term respiratory consequences …

Investigational pharmacological agents for the treatment of ARDS

K Aribindi, M Lim, S Lakshminrusimha… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Acute Respiratory Distress Syndrome (ARDS) is a heterogeneous
form of lung injury with severe hypoxemia and bilateral infiltrates after an inciting event that …

Mesenchymal Stem/Stromal Cells in Asthma Therapy: Mechanisms and Strategies for Enhancement

S Huang, Y Li, J Zeng, N Chang, Y Cheng… - Cell …, 2023 - journals.sagepub.com
Asthma is a complex and heterogeneous disease characterized by chronic airway
inflammation, airway hyperresponsiveness, and airway remodeling. Most asthmatic patients …

Safety and efficacy of mesenchymal stem cells in COVID‐19 patients: A systematic review and meta‐analysis

C Yan, M Hu, R Dai - Immunity, Inflammation and Disease, 2023 - Wiley Online Library
Abstract Background Coronavirus disease‐19 (COVID‐19) is a zoonotic disease that has
become a global pandemic. The fast evolution of the COVID‐19 pandemic and persist …

Effectiveness of RCTs Pooling Evidence on Mesenchymal Stem Cell (MSC) Therapeutic Applications During COVID-19 Epidemic: A Systematic Review

UR Kandula, AD Wake - Biologics: Targets and Therapy, 2023 - Taylor & Francis
Background Global pandemic identified as coronavirus disease 2019 (COVID-19) has
resulted in a variety of clinical symptoms, from asymptomatic carriers to those with severe …

[HTML][HTML] Next-generation treatments: Immunotherapy and advanced therapies for COVID-19

JA Arevalo-Romero, SM Chingaté-López, BA Camacho… - Heliyon, 2024 - cell.com
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), emerged in 2019 following prior outbreaks of coronaviruses like SARS and …

Feasibility study of cord tissue derived mesenchymal stromal cells in COVID-19-related acute respiratory distress syndrome

BH Shaz, BD Kraft, JD Troy, E Poehlein… - Stem cells …, 2023 - academic.oup.com
Background Treatment options for patients with COVID-19-related acute respiratory distress
syndrome (ARDS) are desperately needed. Allogeneic human umbilical cord derived …

Understanding the role of mesenchymal stromal cells in treating COVID-19 acute respiratory distress syndrome

CM O'Kane, MA Matthay - … Journal of Respiratory and Critical Care …, 2023 - atsjournals.org
Considerable experimental evidence has indicated that allogeneic mesenchymal stromal
cells (MSCs) isolated from bone marrow or umbilical cord might be effective for treating …