COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

The β common chain cytokines GM-CSF, IL-3, and IL-5 regulate varied inflammatory
responses that promote the rapid clearance of pathogens but also contribute to pathology in …

The granulocyte-macrophage colony-stimulating factor (GM-CSF) was initially classified as a
hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) …

Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Background Hypereosinophilic syndrome is a group of diseases defined by marked
eosinophilia in blood or tissue and eosinophil-related clinical manifestations. Benralizumab …

Summary The lnterleukln-2 (IL-2) receptor y chain (IL-S&) is a component of high and
Intermediate affinity IL-2 receptors that is required to achieve full ligand binding affinity and …

Abstract THE IDIOPATHIC hypereosinophilic syndrome (HES) is a leukoproliferative
disorder, or more likely disorders, marked by a sustained overproduction of eosinophils. The …

The production of hematopoietic cells is under the tight control of a group of hematopoietic
cytokines. Each cytokine has multiple actions mediated by receptors whose cytoplasmic …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …

Many cytokines and cytokine receptors involved in the regulation of hematopoiesis, immune
responses, and inflammation have been identified and characterized at the molecular level …