Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies

A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications

N Potere, MG Del Buono, R Caricchio, PC Cremer… - …, 2022 - thelancet.com
A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …

Programmed cell death: the pathways to severe COVID-19?

SM Bader, JP Cooney, M Pellegrini… - Biochemical …, 2022 - portlandpress.com
Two years after the emergence of SARS-CoV-2, our understanding of COVID-19 disease
pathogenesis is still incomplete. Despite unprecedented global collaborative scientific efforts …

Mechanisms of COVID-19-induced kidney injury and current pharmacotherapies

WH Faour, A Choaib, E Issa, FE Choueiry… - Inflammation …, 2022 - Springer
The COVID-19 pandemic created a worldwide debilitating health crisis with the entire
humanity suffering from the deleterious effects associated with the high infectivity and …

Multisystem inflammatory syndrome and autoimmune diseases following COVID-19: molecular mechanisms and therapeutic opportunities

P Hosseini, MS Fallahi, G Erabi, M Pakdin… - Frontiers in molecular …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

[HTML][HTML] Invasive pulmonary aspergillosis associated with viral pneumonitis

IMW Dewi, NAF Janssen, D Rosati, M Bruno… - Current opinion in …, 2021 - Elsevier
Highlights•Invasive pulmonary aspergillosis (IPA) can complicate severe influenza and
coronavirus disease 2019 (COVID-19).•IAPA and CAPA pathogenesis share features such …

Biomarkers during COVID-19: mechanisms of change and implications for patient outcomes

CH Chen, SW Lin, CF Shen, KS Hsieh, CM Cheng - Diagnostics, 2022 - mdpi.com
As the COVID-19 (Coronavirus disease 19) pandemic spreads worldwide, the massive
numbers of COVID-19 patients have created a considerable healthcare burden for every …

Pyroptosis and its role in SARS-CoV-2 infection

ZA Bittner, M Schrader, SE George, R Amann - Cells, 2022 - mdpi.com
The pore-forming inflammatory cell death pathway, pyroptosis, was first described in the
early 1990s and its role in health and disease has been intensively studied since. The …

Anakinra in hospitalized non-intubated patients with coronavirus disease 2019: a systematic review and meta-analysis

F Barkas, S Filippas-Ntekouan, M Kosmidou… - …, 2021 - academic.oup.com
Objectives Acute respiratory distress syndrome and cytokine release syndrome are the
major complications of coronavirus disease 2019 (COVID-19) associated with increased …