Dietary polyphenols and their role in oxidative stress-induced human diseases: Insights into protective effects, antioxidant potentials and mechanism (s) of action

M Rudrapal, SJ Khairnar, J Khan, AB Dukhyil… - Frontiers in …, 2022 - frontiersin.org
Dietary polyphenols including phenolic acids, flavonoids, catechins, tannins, lignans,
stilbenes, and anthocyanidins are widely found in grains, cereals, pulses, vegetables …

Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease

V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

[HTML][HTML] Oxidative stress–Complex pathological issues concerning the hallmark of cardiovascular and metabolic disorders

D Rotariu, EE Babes, DM Tit, M Moisi, C Bustea… - Biomedicine & …, 2022 - Elsevier
Oxidative stress is a complex biological process characterized by the excessive production
of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …

Oxidative stress: harms and benefits for human health

G Pizzino, N Irrera, M Cucinotta, G Pallio… - Oxidative medicine …, 2017 - Wiley Online Library
Oxidative stress is a phenomenon caused by an imbalance between production and
accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a …

Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

[HTML][HTML] Free radicals, antioxidants in disease and health

LA Pham-Huy, H He, C Pham-Huy - International journal of …, 2008 - ncbi.nlm.nih.gov
Free radicals and oxidants play a dual role as both toxic and beneficial compounds, since
they can be either harmful or helpful to the body. They are produced either from normal cell …

Neuroprotective effects and therapeutic potential of the citrus flavonoid hesperetin in neurodegenerative diseases

JA Evans, P Mendonca, KFA Soliman - Nutrients, 2022 - mdpi.com
Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance

AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

Carotenoids in human skin in vivo: Antioxidant and photo-protectant role against external and internal stressors

ME Darvin, J Lademann, J von Hagen, SB Lohan… - Antioxidants, 2022 - mdpi.com
The antioxidant system of the human body plays a crucial role in maintaining redox
homeostasis and has an important protective function. Carotenoids have pronounced …

Battle between plants as antioxidants with free radicals in human body

F Jamshidi-Kia, JP Wibowo, M Elachouri… - Journal of Herbmed …, 2020 - research.rug.nl
Free radicals are constructed by natural physiological activities in the human cells as well as
in the environment. They may be produced as a result of diet, smoking, exercise …