Endophenotypes are intermediate phenotypes on the putative causal pathway from
genotype to phenotype and can aid in discovering the genetic etiology of a disorder. There …

One of four children in the United States lives in a family in which the child is exposed to
alcoholism. Children of alcoholics (COAs) are two to ten times more likely to develop …

Background The children of parents who abuse alcohol typically show reduced amplitude of
the P3 event-related potential wave. We determined if this effect was present in a population …

Alcohol use is common during the ages of 13 to 18, the stage commonly referred to as
adolescence. An annual survey of US. high school students revealed that in 2002, 18% of …

Alcohol-dependence is often associated with comorbid psychiatric symptoms. However, the
results concerning the influence of these symptoms on cognitive functioning in alcoholism …

Abstract Objective The P300 ERP component is a marker of reduced capacity in alcohol use
disorder (AUD) to engage attentional mechanisms and update memory representations. No …

Because alcoholism is a multi-factorial psychiatric disorder, with both psychosocial and
biochemical/genetic factors leading to its manifestation in any one individual, the presence …

Background: The P3b component of the event-related potential (ERP) has frequently been
reported to be reduced in children and adolescents at high risk for developing alcoholism …

Background: The robust association of alcoholism with reduced P300 event‐related
potential amplitude has been largely established in severely affected alcoholics and their …

Native Americans have some of the highest rates of alcohol abuse and dependence, yet risk
factors for problem drinking remain relatively unknown. The amplitude of the P3 component …