Purpose The purpose of this review was to assess the effectiveness of pelvic floor muscle
training (PFMT) in the treatment of urinary incontinence (UI) in women, with a particular …

Background. A number of studies have computed the minimally important difference (MID)
for health-related quality of life instruments. Objective. To determine whether there is …

Objective: The purpose of this study was to assess the construct validity of two global
assessment questions, the Patient Global Impression of Severity and of Improvement, in …

Purpose: We assessed the efficacy, safety and effects on quality of life of
onabotulinumtoxinA in patients with neurogenic detrusor overactivity. Materials and …

A lack of clarity exists about the definition and adequate approach for evaluating
responsiveness. An overview is presented of different categories of definitions and methods …

Background Urinary incontinence (UI) is a common disorder that is increasingly important as
our population ages. Less is known about UI in younger women, and few large surveys have …

OBJECTIVE: There has been growing interest in the investigation of health-related quality of
life (HRQOL) among patients with gastrointestinal (GI) disorders. We recently reported on …

Objective: This report extracts important considerations for determining and applying
clinically significant differences in quality of life (QOL) measures from six published articles …

Background No drugs are approved for treatment of premature ejaculation. Our aim was to
determine the efficacy and tolerability of on-demand dapoxetine in patients with severe …

Background: Urinary incontinence is a highly prevalent and burdensome condition among
women. However, fewer than half of women with symptoms talk to a physician about …