Hantavirus in humans: a review of clinical aspects and management

PA Vial, M Ferrés, C Vial, J Klingström… - The Lancet Infectious …, 2023 - thelancet.com
Hantavirus infections are part of the broad group of viral haemorrhagic fevers. They are also
recognised as a distinct model of an emergent zoonotic infection with a global distribution …

Neutralization Determinants on Poxviruses

V Riccardo, GC Pablo - Viruses, 2023 - mdpi.com
Smallpox was a highly contagious disease caused by the variola virus. The disease affected
millions of people over thousands of years and variola virus ranked as one of the deadliest …

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody

E Mittler, A Serris, ES Esterman, C Florez… - Science translational …, 2023 - science.org
Emerging rodent-borne hantaviruses cause severe diseases in humans with no approved
vaccines or therapeutics. We recently isolated a monoclonal broadly neutralizing antibody …

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

TB Engdahl, E Binshtein, RL Brocato, NA Kuzmina… - Elife, 2023 - elifesciences.org
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to
humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections …

Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody

R Stass, TB Engdahl, NS Chapman, RM Wolters… - Nature …, 2023 - nature.com
Rodent-borne hantaviruses are prevalent worldwide and upon spillover to human
populations, cause severe disease for which no specific treatment is available. A potent …

Characterization of a panel of cross-reactive Hantavirus Nucleocapsid protein-specific monoclonal antibodies

A Avižinienė, I Kučinskaitė-Kodzė… - Viruses, 2023 - mdpi.com
Hantaviruses are emerging pathogens with a worldwide distribution that can cause life-
threatening diseases in humans. Monoclonal antibodies (MAbs) against hantavirus …

Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies

A Tuiskunen Bäck, J Rasmuson, T Thunberg… - Infectious …, 2022 - Taylor & Francis
Background Orthohantaviruses are rodent-borne emerging viruses that cause haemorrhagic
fever with renal syndrome (HFRS) in Eurasia and hantavirus pulmonary syndrome in …

The Adaptive Immune Response against Bunyavirales

R Alatrash, BB Herrera - Viruses, 2024 - mdpi.com
The Bunyavirales order includes at least fourteen families with diverse but related viruses,
which are transmitted to vertebrate hosts by arthropod or rodent vectors. These viruses are …

Andes Virus Genome Mutations That Are Likely Associated with Animal Model Attenuation and Human Person-to-Person Transmission

CM Bellomo, DO Alonso, U Pérez-Sautu, K Prieto… - Msphere, 2023 - Am Soc Microbiol
We performed whole-genome sequencing with bait enrichment techniques to analyze
Andes virus (ANDV), a cause of human hantavirus pulmonary syndrome. We used …

[HTML][HTML] Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38

OS Shin, SR Monticelli, CK Hjorth, V Hornet, M Doyle… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Crimean-Congo hemorrhagic fever virus can cause lethal disease in humans yet there are
no approved medical countermeasures. Viral glycoprotein GP38, unique to Nairoviridae, is a …