[HTML][HTML] Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

[HTML][HTML] DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy

R Huang, PK Zhou - Signal transduction and targeted therapy, 2021 - nature.com
Genomic instability is the hallmark of various cancers with the increasing accumulation of
DNA damage. The application of radiotherapy and chemotherapy in cancer treatment is …

[HTML][HTML] Determination of Antioxidants by DPPH Radical Scavenging Activity and Quantitative Phytochemical Analysis of Ficus religiosa

S Baliyan, R Mukherjee, A Priyadarshini, A Vibhuti… - Molecules, 2022 - mdpi.com
The use of F. religiosa might be beneficial in inflammatory illnesses and can be used for a
variety of health conditions. In this article, we studied the identification of antioxidants using …

Biomarkers of oxidative stress and antioxidant defense

S Demirci-Cekic, G Özkan, AN Avan, S Uzunboy… - … of pharmaceutical and …, 2022 - Elsevier
A number of reactive oxygen and nitrogen species are produced during normal metabolism
in human body. These species can be both radical and non-radical and have varying …

[HTML][HTML] RONS and oxidative stress: An overview of basic concepts

AK Aranda-Rivera, A Cruz-Gregorio… - Oxygen, 2022 - mdpi.com
Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …

[HTML][HTML] Chronic inflammation and the hallmarks of aging

JJ Baechle, N Chen, P Makhijani, S Winer… - Molecular …, 2023 - Elsevier
Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

Hydroxyl radical is a significant player in oxidative DNA damage in vivo

B Halliwell, A Adhikary, M Dingfelder… - Chemical Society …, 2021 - pubs.rsc.org
Recent publications have suggested that oxidative DNA damage mediated by hydroxyl
radical (˙ OH) is unimportant in vivo, and that carbonate anion radical (CO3˙−) plays the key …

[HTML][HTML] The role of cellular reactive oxygen species in cancer chemotherapy

H Yang, RM Villani, H Wang, MJ Simpson… - Journal of experimental …, 2018 - Springer
Most chemotherapeutics elevate intracellular levels of reactive oxygen species (ROS), and
many can alter redox-homeostasis of cancer cells. It is widely accepted that the anticancer …

Nanocatalytic tumor therapy by single-atom catalysts

M Huo, L Wang, Y Wang, Y Chen, J Shi - ACS nano, 2019 - ACS Publications
Initiating localized catalytic chemical reactions in tumor microenvironment (TME) can
achieve appealing tumor-therapeutic efficacy concurrently with high specificity and desirable …

Measurement and clinical significance of biomarkers of oxidative stress in humans

I Marrocco, F Altieri, I Peluso - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …