The SARS-CoV-2 as an instrumental trigger of autoimmunity

A Dotan, S Muller, D Kanduc, P David, G Halpert… - Autoimmunity …, 2021 - Elsevier
Autoimmunity may be generated by a variety of factors by creating a hyper-stimulated state
of the immune system. It had been established long ago that viruses are a substantial …

NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

New-onset IgG autoantibodies in hospitalized patients with COVID-19

SE Chang, A Feng, W Meng, SA Apostolidis… - Nature …, 2021 - nature.com
COVID-19 is associated with a wide range of clinical manifestations, including autoimmune
features and autoantibody production. Here we develop three protein arrays to measure IgG …

The systemic inflammation index on admission predicts in-hospital mortality in COVID-19 patients

AG Fois, P Paliogiannis, V Scano, S Cau, S Babudieri… - Molecules, 2020 - mdpi.com
Background. The rapid onset of a systemic pro-inflammatory state followed by acute
respiratory distress syndrome is the leading cause of mortality in patients with COVID-19 …

COVID-19 and thrombosis: From bench to bedside

MAM Ali, SA Spinler - Trends in cardiovascular medicine, 2021 - Elsevier
Abstract Coronavirus disease of 2019 (COVID-19) is the respiratory viral infection caused by
the coronavirus SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus 2). Despite …

Innate immune sensing of coronavirus and viral evasion strategies

Y Kasuga, B Zhu, KJ Jang, JS Yoo - Experimental & molecular medicine, 2021 - nature.com
The innate immune system is the first line of the host defense program against pathogens
and harmful substances. Antiviral innate immune responses can be triggered by multiple …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

[HTML][HTML] Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

C Radermecker, N Detrembleur, J Guiot… - Journal of Experimental …, 2020 - rupress.org
Infection with SARS-CoV-2 is causing a deadly and pandemic disease called coronavirus
disease–19 (COVID-19). While SARS-CoV-2–triggered hyperinflammatory tissue-damaging …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

[HTML][HTML] Neutrophils and COVID-19: The road so far

LHA Cavalcante-Silva, DCM Carvalho… - International …, 2021 - Elsevier
The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-
19, a pandemic disease. This disease is characterized by acute respiratory distress …