Bile acids are cholesterol-derived surfactants that circulate actively between the liver and
ileum and that are classically recognized for emulsifying dietary lipids to facilitate absorption …

Organic anion transporting polypeptide (OATP) family transporters accept a number of drugs
and are increasingly being recognized as important factors in governing drug and …

The properties of intestinal folate absorption were documented decades ago. However, it
was only recently that the proton-coupled folate transporter (PCFT) was identified and its …

Organic anion-transporting polypeptides or OATPs are central transporters in the disposition
of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of …

One approach to experimental science involves creating hypotheses, then testing them by
varying one or more independent variables, and assessing the effects of this variation on the …

Quercetin is a flavonoid, its glycosides and aglycone are found in significant amounts in
several plants and dietary supplements. Because of the high presystemic biotransformation …

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic
transporters that mediate the uptake of many clinically important drugs, including statins from …

Luteolin and naringenin are flavonoids found in various foods/beverages and present in
certain dietary supplements. After a high intake of these flavonoids, their sulfate and …

A recent paper in this journal sought to counter evidence for the role of transport proteins in
effecting drug uptake into cells, and questions that transporters can recognize drug …

Recent studies of membrane transporters have revealed their importance in determining the
pharmacokinetics of transporter substrates. When drug-drug interactions (DDIs) or genetic …