Abstract Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to
global healthcare, worsening outcomes and increasing mortality among infected patients …

Intra-abdominal infections (IAI) are among the most common global healthcare challenges
and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their …

Background Rapid and widespread increases in carbapenem resistance (CR) necessitate
identification of risk factors to guide appropriate interventions. Objectives We aimed to …

Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health,
leading to rising health care costs, morbidity and mortality. Multidrug-resistance is commonly …

The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase
producing Enterobacteriaceae (ESBL-E), poses a significant global health challenge as it …

Purpose Fracture-related infection (FRI) is an important complication related to orthopaedic
trauma. Although the scientific interest with respect to the diagnosis and treatment of FRI is …

While antibiotic resistance is rising to dangerously high levels, resistance mechanisms are
spreading globally among diverse bacterial species. The emergence of antibiotic-resistant …

Escherichia coli is a versatile commensal and pathogenic member of the human microflora.
As the primary causative pathogen in urosepsis, E. coli places an immense burden on …

(1) Background: Piperacillin-tazobactam represents the first-line option for treating infections
caused by full-or multi-susceptible Enterobacterales and/or Pseudomonas aeruginosa in …

ESKAPE bacteria represent a group of opportunistic bacterial pathogens that display
widespread antimicrobial resistance, including resistance to the last-line antibiotics, thereby …