Pathways of coagulation/fibrinolysis activation in malignancy

LR Zacharski, MZ Wojtukiewicz… - … in thrombosis and …, 1992 - thieme-connect.com
Critical information on the nature of the coagulation-cancer interaction has been obtained
from a number of sources. In vitro/ex vivo sources of information include assays performed …

The role of fibrin in tumor metastasis

V Costantini, LR Zacharski - Cancer and Metastasis Reviews, 1992 - Springer
A volume of data that has accumulated for over a century has suggested that fibrin may
facilitate the persistence and progression of malignancy. Techniques that have been …

Abnormal regulation of coagulation/fibrinolysis in small cell carcinoma of the lung

MZ Wojtukiewicz, LR Zacharski, VA Memoli, W Kisiel… - Cancer, 1990 - Wiley Online Library
Components of coagulation and fibrinolysis reactions were identified in situ by
immunohistochemical staining in fresh frozen sections of small cell carcinoma of the lung …

Indirect activation of blood coagulation in colon cancer

MZ Wojtukiewicz, LR Zacharski… - Thrombosis and …, 1989 - thieme-connect.com
Systemic activation of the coagulation mechanism is known to exist in patients with colon
cancer. The mechanism of such activation was investigated using immunohistochemical …

Urokinase combination chemotherapy in small cell lung cancer. A phase II study

FA Calvo, OF Hidalgo, F Gonzalez, J Rebollo… - Cancer, 1992 - Wiley Online Library
Abstract Background and Methods. Fifty‐one patients with small cell lung cancer (SCLC)
were treated with alternating urokinase (UK)‐cyclophosphamide‐doxorubicin (Adriamycin …

Clinical trials with anticoagulant and antiplatelet therapies

LR Zacharski, KR Meehan, SM Algarra… - Cancer and Metastasis …, 1992 - Springer
Clinical trials of drugs that influence coagulation and fibrinolysis pathways have been
undertaken in patients with malignancy because these pathways are capable of influencing …

Antithrombotic therapy in gynecologic surgery and gynecologic oncology

GF von Tempelhoff, L Heilmann - Hematology/Oncology …, 2000 - hemonc.theclinics.com
At the European Consensus Conference held in Windsor, UK, in November 1991, 16 a
moderate risk for the development of venous thrombosis (VT) was postulated for most …

Treatment of malignancy by activation of the plasminogen system

LR Zacharski, DL Ornstein, EC Gabazza… - … in thrombosis and …, 2002 - thieme-connect.com
The blood coagulation mechanism in general and the plasminogen system in particular
contribute to malignant growth and dissemination in complex ways. This article reviews the …

Registry of clinical trials of antithrombotic drugs in cancer: second report

LR Zacharski, MB Donati… - Thrombosis and …, 1993 - thieme-connect.com
The Subcommittee on Hemostasis and Malignancy of the Scientific and Standardization
Committee determined at its meeting of July 8, L992, to update the registry of clinical trials of …

The coagulation biology of cancer

LR Zacharski, AL Howell, VA Memoli - Fibrinolysis, 1992 - Elsevier
It is common knowledge that blood coagulation and fibrinolysis are activated systemically in
patients with malignancy. Studies in specific in vitro and animal models of malignancy have …