The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review

I Mohammed, A Nauman, P Paul… - Human vaccines & …, 2022 - Taylor & Francis
With the relatively rapid development of the COVID-19 pandemic, vaccine development has
become crucial for limiting disease transmission. The accelerated growth in the approved …

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Z Wang, KD Popowski, D Zhu… - Nature biomedical …, 2022 - nature.com
The first two mRNA vaccines against infection by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) that were approved by regulators require a cold chain and …

[HTML][HTML] Humoral and cellular immune memory to four COVID-19 vaccines

Z Zhang, J Mateus, CH Coelho, JM Dan… - Cell, 2022 - cell.com
Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect
against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B …

[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

BE Jones, PL Brown-Augsburger, KS Corbett… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health
threat for which preventive and therapeutic agents are urgently needed. Neutralizing …

BNT162b vaccines protect rhesus macaques from SARS-CoV-2

AB Vogel, I Kanevsky, Y Che, KA Swanson, A Muik… - Nature, 2021 - nature.com
A safe and effective vaccine against COVID-19 is urgently needed in quantities that are
sufficient to immunize large populations. Here we report the preclinical development of two …

Correlates of protection against SARS-CoV-2 in rhesus macaques

K McMahan, J Yu, NB Mercado, C Loos, LH Tostanoski… - Nature, 2021 - nature.com
Recent studies have reported the protective efficacy of both natural and vaccine-induced,,,,–
immunity against challenge with severe acute respiratory syndrome coronavirus 2 (SARS …

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

JM Dan, J Mateus, Y Kato, KM Hastie, ED Yu, CE Faliti… - Science, 2021 - science.org
INTRODUCTION Immunological memory is the basis for durable protective immunity after
infections or vaccinations. Duration of immunological memory after severe acute respiratory …

[HTML][HTML] Acceptance of the COVID-19 vaccine based on the health belief model: A population-based survey in Hong Kong

MCS Wong, ELY Wong, J Huang, AWL Cheung, K Law… - Vaccine, 2021 - Elsevier
Background Vaccines for COVID-19 are anticipated to be available by 2021. Vaccine uptake
rate is a crucial determinant for herd immunity. We examined factors associated with …

[HTML][HTML] The limitless future of RNA therapeutics

TR Damase, R Sukhovershin, C Boada… - … in bioengineering and …, 2021 - frontiersin.org
Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …