Mutual regulation between N6-methyladenosine (m6A) modification and circular RNAs in cancer: impacts on therapeutic resistance

H Lin, Y Wang, P Wang, F Long, T Wang - Molecular cancer, 2022 - Springer
The resistance of tumor cells to therapy severely impairs the efficacy of treatment, leading to
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …

[HTML][HTML] LncRNA-miRNA axis in tumor progression and therapy response: An emphasis on molecular interactions and therapeutic interventions

M Entezari, A Taheriazam, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …

Novel insights into mutual regulation between N6-methyladenosine modification and LncRNAs in tumors

N Zhang, Y Sun, Z Mei, Z He, S Gu - Cancer Cell International, 2023 - Springer
Abstract N6-methyladenosine (m6A), one of the most common RNA methylation
modifications, has emerged in recent years as a new layer of the regulatory mechanism …

METTL16 epigenetically enhances GPX4 expression via m6A modification to promote breast cancer progression by inhibiting ferroptosis

F Ye, J Wu, F Zhang - Biochemical and Biophysical Research …, 2023 - Elsevier
Breast cancer is malignant cancer that severely threatens the life quality of female patients.
N6-methyladenosine (m6A) is a prevalent modification of RNA. METTL16 is an important …

N6-methyladenosine (m6A) methyltransferase METTL3 regulates sepsis-induced myocardial injury through IGF2BP1/HDAC4 dependent manner

H Shen, K Xie, M Li, Q Yang, X Wang - Cell death discovery, 2022 - nature.com
Recent studies have identified that N6-methyladenosine (m6A) extensively participates in
the myocardial injury pathophysiological process. However, the role of m6A on sepsis …

m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling

X Wang, Y Liu, M Zhou, L Yu, Z Si - Journal of Experimental & Clinical …, 2023 - Springer
Background Liver metastasis is one of the most important reasons for high mortality of
colorectal cancer (CRC). Growing evidence illustrates that lncRNAs play a critical role in …

m6A methylation-mediated regulation of LncRNA MEG3 suppresses ovarian cancer progression through miR-885-5p and the VASH1 pathway

Y Li, S Lou, J Zhang, S Zhao, G Lou - Journal of Translational Medicine, 2024 - Springer
Background Ovarian cancer poses a serious threat to women's health. Due to the difficulty of
early detection, most patients are diagnosed with advanced-stage disease or peritoneal …

Interactions between circRNA and protein in breast cancer

B Yang, YW Wang, K Zhang - Gene, 2023 - Elsevier
Circular RNA (circRNA) is a newly discovered endogenous non-coding RNA that plays
important roles in the occurrence and development of various cancers. Current research …

Implications of m6A methylation and microbiota interaction in non-small cell lung cancer: From basics to therapeutics

FS Qiu, JQ He, YS Zhong, MY Guo… - Frontiers in Cellular and …, 2022 - frontiersin.org
N6-methyladenine (m6A) is one of the most common RNA epigenetic modifications in all
higher eukaryotes. Increasing evidence demonstrated that m6A-related proteins, acted as …

The potential value of M6a rna methylation in the development of cancers focus on malignant glioma

F Chen, X Xie, M Chao, H Cao, L Wang - Frontiers in immunology, 2022 - frontiersin.org
N6-methyladenosine (m6A) RNA methylation is an epigenetic modification that has
emerged in the last few years and has received increasing attention as the most abundant …