Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

The quality and maturation of an oocyte not only play decisive roles in fertilization and
embryo success, but also have long-term impacts on the later growth and development of …

A serine/threonine-specific protein kinase B (PKB), also known as Akt, is a key factor in the
phosphoinositide 3-kinase (PI3K)/Akt signaling pathway that regulates cell survival …

The accumulation and storage of maternal mRNA is crucial for oocyte maturation and
embryonic development. PATL2 is an oocyte-specific RNA-binding protein, and previous …

Aneuploidy seriously compromises female fertility and increases incidence of birth defects.
Rates of aneuploidy in human eggs from even young women are significantly higher than …

Centrosomes are the main microtubule-organizing centers in animal cells. Due to the
semiconservative nature of centrosome duplication, the two centrosomes differ in age. In …

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant digestive tract tumor with
limited clinical treatments. Transforming acidic coiled-coil-containing protein 3 (TACC3) is a …

Oocyte maturation defect can lead to maternal reproduction disorder. NAMPT is a rate‐
limiting enzyme in mammalian NAD+ biosynthesis pathway, which can regulate a variety of …

Transforming acidic acid coiled-coil protein 3 (TACC3) and cytoskeleton associated protein
5 (cKAP5; or colonic hepatic tumor overexpressed gene, chTOG) are vital for spindle …

STUDY QUESTION Which actively translated maternal transcripts are differentially regulated
between clinically relevant in vitro and in vivo maturation (IVM) conditions in mouse oocytes …