The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an
exquisite control of exchange of compounds between the blood and the brain parenchyma …

Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Stroke remains a major cause of long-term disability and mortality worldwide. The immune
system plays an important role in determining the condition of the brain following stroke. As …

Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Objective Ischemic stroke is one of the leading causes of death globally, and inflammation is
considered as a vital contributor to the pathophysiology of ischemic stroke. Recently …

Simple Summary Amyotrophic lateral sclerosis (ALS) is a disease characterized by the
death of motor neurons that results in progressive muscle weakness and paralysis …

Alzheimer's disease (AD) is the most common progressive and irreversible
neurodegeneration characterized by the impairment of memory and cognition. Despite years …

Stroke is a common disease in clinical practice, which seriously endangers people's
physical and mental health. The neurovascular unit (NVU) plays a key role in the occurrence …

Brain tumors represent the leading cause of disease-related mortality and morbidity in
children, with effective treatments urgently required. One factor limiting the effectiveness of …

The polarization of microglia plays an important role in the outcome of ischemic stroke (IS).
In the aged population, senescent microglia show a predominant pro-inflammatory …