Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Acute management of traumatic brain injury

MA Vella, ML Crandall, MB Patel - Surgical Clinics, 2017 - surgical.theclinics.com
Trauma is the leading cause of death in individuals aged 1 to 45 years, with traumatic brain
injury (TBI) responsible for most these deaths; more than 50,000 deaths per year in the …

A manual for the glasgow outcome scale-extended interview

L Wilson, K Boase, LD Nelson, NR Temkin… - Journal of …, 2021 - liebertpub.com
The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used
outcome instruments to assess global disability and recovery after traumatic brain injury …

Contusion progression following traumatic brain injury: a review of clinical and radiological predictors, and influence on outcome

K Adatia, VFJ Newcombe, DK Menon - Neurocritical care, 2021 - Springer
Secondary injuries remain an important cause of the morbidity and mortality associated with
traumatic brain injury (TBI). Progression of cerebral contusions occurs in up to 75% of …

A state-of-the-science overview of randomized controlled trials evaluating acute management of moderate-to-severe traumatic brain injury

P Bragge, A Synnot, AI Maas, DK Menon… - Journal of …, 2016 - liebertpub.com
Moderate-to-severe traumatic brain injury (TBI) remains a major global challenge, with rising
incidence, unchanging mortality and lifelong impairments. State-of-the-science reviews are …

Management and challenges of severe traumatic brain injury

S Rakhit, MF Nordness, SR Lombardo… - … in respiratory and …, 2021 - thieme-connect.com
Traumatic brain injury (TBI) is the leading cause of death and disability in trauma patients,
and can be classified into mild, moderate, and severe by the Glasgow coma scale (GCS) …

Blossoming contusions: identifying factors contributing to the expansion of traumatic intracerebral hemorrhage

JA Carnevale, DJ Segar, AY Powers, M Shah… - Journal of …, 2018 - thejns.org
OBJECTIVE Traumatic brain injury (TBI) remains a significant cause of neurological
morbidity and mortality. Each year, more than 1.7 million patients present to the emergency …

Pre-clinical testing of therapies for traumatic brain injury

DS DeWitt, BE Hawkins, CE Dixon… - Journal of …, 2018 - liebertpub.com
Despite the large number of promising neuroprotective agents identified in experimental
traumatic brain injury (TBI) studies, none has yet shown meaningful improvements in long …

Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study

TA Van Essen, HF Den Boogert, MC Cnossen… - Acta …, 2019 - Springer
Background Neurosurgical management of traumatic brain injury (TBI) is challenging, with
only low-quality evidence. We aimed to explore differences in neurosurgical strategies for …

Surgical decision making in brain hemorrhage: new analysis of the STICH, STICH II, and STITCH (Trauma) randomized trials

BA Gregson, P Mitchell, AD Mendelow - Stroke, 2019 - Am Heart Assoc
Background and Purpose—The STICH (Surgical Trial in Lobar Intracerebral Haemorrhage) I
and II trials randomized patients with spontaneous intracerebral hemorrhage (ICH) to early …