[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to
severe acute respiratory distress. The severity of the illness can also extend from mild …

[HTML][HTML] COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …

[HTML][HTML] COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) followed by repair with lung remodeling is
observed in COVID-19. These findings can lead to pulmonary terminal fibrosis, a form of …

Risk of severe coronavirus disease 2019 in patients with inflammatory bowel disease in the United States: a multicenter research network study

S Singh, A Khan, M Chowdhry, M Bilal… - …, 2020 - gastrojournal.org
Methods This was a population-based retrospective cohort study conducted using TriNetX
(Cambridge, MA), a federated health research network data set. We performed a real-time …

[HTML][HTML] Lactoferrin as antiviral treatment in COVID-19 management: preliminary evidence

E Campione, C Lanna, T Cosio, L Rosa… - International journal of …, 2021 - mdpi.com
Lactoferrin (Lf), a multifunctional cationic glycoprotein synthesized by exocrine glands and
neutrophils, possesses an in vitro antiviral activity against SARS-CoV-2. Thus, we conducted …

[HTML][HTML] Diverse effects of exosomes on COVID-19: a perspective of progress from transmission to therapeutic developments

S Gurunathan, MH Kang, JH Kim - Frontiers in immunology, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new strain of
coronavirus and the causative agent of the current global pandemic of coronavirus disease …

[HTML][HTML] Anti-IL6 treatment of serious COVID-19 disease: A monocentric retrospective experience

L Castelnovo, A Tamburello, A Lurati, E Zaccara… - Medicine, 2021 - journals.lww.com
COVID-19 is causing a high influx of patients suffering from serious respiratory
complications leading the necessity to find effective therapies. These patients seem to …

[HTML][HTML] Sleep quality and COVID-19 outcomes: the evidence-based lessons in the framework of predictive, preventive and personalised (3P) medicine

K Richter, S Kellner, T Hillemacher, O Golubnitschaja - EPMA Journal, 2021 - Springer
Sleep quality and duration play a pivotal role in maintaining physical and mental health. In
turn, sleep shortage, deprivation and disorders are per evidence the risk factors and …

[HTML][HTML] COVID-19 is a multi-organ aggressor: epigenetic and clinical marks

MM Kgatle, IO Lawal, G Mashabela… - Frontiers in …, 2021 - frontiersin.org
The progression of coronavirus disease 2019 (COVID-19), resulting from a severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, may be influenced by both …