Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
Such testing and trying time probably never seen before in the human history. The novel
coronavirus disease abbreviated as COVID-19 is the ongoing health crisis which entered …

Targeting Ferroptosis for Lung Diseases: Exploring Novel Strategies in Ferroptosis‐Associated Mechanisms

TL Ma, Y Zhou, C Wang, L Wang… - Oxidative medicine …, 2021 - Wiley Online Library
Ferroptosis is an iron‐dependent regulated necrosis characterized by the peroxidation
damage of lipid molecular containing unsaturated fatty acid long chain on the cell …

[HTML][HTML] CLEC5A is critical in Pseudomonas aeruginosa–induced NET formation and acute lung injury

PS Sung, YC Peng, SP Yang, CH Chiu, SL Hsieh - JCI insight, 2022 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa is one of the most common nosocomial infections worldwide, and
it frequently causes ventilator-associated acute pneumonia in immunocompromised …

[HTML][HTML] Profile of circulatory cytokines and chemokines in human coronaviruses: a systematic review and meta-analysis

A Zawawi, AY Naser, H Alwafi, F Minshawi - Frontiers in Immunology, 2021 - frontiersin.org
Background SARS, MERS, and COVID-19 share similar characteristics. For instance, the
genetic homology of SARS-CoV-2 compared to SARS-CoV and MERS-CoV is 80% and …

Discovery of novel pyrazole derivatives as a potent anti‐inflammatory agent in RAW264. 7 cells via inhibition of NF‐ĸB for possible benefit against SARS‐CoV‐2

A Masih, AK Agnihotri, JK Srivastava… - … of biochemical and …, 2021 - Wiley Online Library
Due to unavailability of a specific drug/vaccine to attenuate severe acute respiratory
syndrome coronavirus 2, the current strategy to combat the infection has been largely …

[HTML][HTML] Critical role of nitric oxide in impeding COVID-19 transmission and prevention: a promising possibility

R Rajendran, A Chathambath, AG Al-Sehemi… - … Science and Pollution …, 2022 - Springer
COVID-19 is a serious respiratory infection caused by a beta-coronavirus that is closely
linked to SARS. Hypoxemia is a symptom of infection, which is accompanied by acute …

[HTML][HTML] Neurological implications of COVID-19: role of redox imbalance and mitochondrial dysfunction

RK Kaundal, AK Kalvala, A Kumar - Molecular Neurobiology, 2021 - Springer
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 or COVID-19 has been
declared as a pandemic disease by the World Health Organization (WHO). Globally, this …

Neurological manifestations and pathogenic mechanisms of COVID-19

M Galea, M Agius, N Vassallo - Neurological research, 2022 - Taylor & Francis
ABSTRACT Coronavirus disease (COVID-19) arising from severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) viral infection has caused a worldwide pandemic …

Scientific hypothesis and rational pharmacological for the use of sacubitril/valsartan in cardiac damage caused by COVID-19

A Vitiello, R La Porta, F Ferrara - Medical Hypotheses, 2021 - Elsevier
Abstract On March 11, 2020 the World Health Organization (WHO) declared the state of
global pandemic caused by the new SARS-CoV-2 (COVID-19). To date, no antivirals …

[HTML][HTML] Deleterious effects of nervous system in the offspring following maternal SARS-CoV-2 infection during the COVID-19 pandemic

R Wang, Z Wu, C Huang, K Hashimoto, L Yang… - Translational …, 2022 - nature.com
During the Coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is universally susceptible to all types of populations …