GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism

L Rochette, M Zeller, Y Cottin, C Vergely - Trends in Endocrinology & …, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of
respiratory and cardiovascular diseases, known as coronavirus disease 2019 (COVID-19) …

Safety and efficacy of convalescent plasma in COVID-19: an overview of systematic reviews

M Franchini, F Corsini, D Focosi, M Cruciani - Diagnostics, 2021 - mdpi.com
Convalescent plasma (CP) from patients recovered from COVID-19 is one of the most
studied anti-viral therapies against SARS-COV-2 infection. The aim of this study is to …

Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect pharmacokinetics

C Ambrus, É Bakos, B Sarkadi, C Özvegy-Laczka… - Scientific Reports, 2021 - nature.com
Transporters in the human liver play a major role in the clearance of endo-and xenobiotics.
Apical (canalicular) transporters extrude compounds to the bile, while basolateral …

Potential therapeutic approach of melatonin against omicron and some other variants of SARS-CoV-2

R Begum, ANM Mamun-Or-Rashid, TT Lucy… - Molecules, 2022 - mdpi.com
The Omicron variant (B. 529) of COVID-19 caused disease outbreaks worldwide because of
its contagious and diverse mutations. To reduce these outbreaks, therapeutic drugs and …

Efficacy of high-dose polyclonal intravenous immunoglobulin in COVID-19: A systematic review

D Focosi, M Franchini, M Tuccori, M Cruciani - Vaccines, 2022 - mdpi.com
Background: Although several therapeutic strategies have been investigated, the optimal
treatment approach for patients with coronavirus disease (COVID-19) remains to be …

[HTML][HTML] Changes in the blood viscosity in patients with SARS-CoV-2 infection

HM Al-Kuraishy, AI Al-Gareeb, SM Al-Hamash… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by a novel virus known as severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2-induced …

Pharmacological approaches to pulmonary fibrosis following COVID-19

S Lassan, T Tesar, J Tisonova… - Frontiers in …, 2023 - frontiersin.org
Background: In the past few years, COVID-19 became the leading cause of morbidity and
mortality worldwide. Although the World Health Organization has declared an end to COVID …

Convalescent plasma for hospitalized COVID-19 patients: a single-center experience

M Franchini, C Glingani, GD Donno, G Lucchini… - Life, 2022 - mdpi.com
In Winter 2020, Italy, and in particular the Lombardy region, was the first country in the
Western hemisphere to be hit by the COVID-19 pandemic. Plasma from individuals …

[HTML][HTML] Lessons learned from the use of convalescent plasma for the treatment of COVID-19 and specific considerations for immunocompromised patients

M Beraud, EG Meyer, M Lozano, A Bah… - … and Apheresis Science, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) convalescent plasma (CovCP) infusions
have been widely used for the treatment of hospitalized patients with COVID-19. The aims of …

A clinical update on SARS-CoV-2: Pathology and development of potential inhibitors

DD Singh, I Han, EH Choi, DK Yadav - Current Issues in Molecular …, 2023 - mdpi.com
SARS-CoV-2 (severe acute respiratory syndrome) is highly infectious and causes severe
acute respiratory distress syndrome (SARD), immune suppression, and multi-organ failure …