Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

[HTML][HTML] The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches

A Varesi, LIM Campagnoli, S Chirumbolo… - Pharmacological …, 2023 - Elsevier
Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …

Anti-inflammatory, antioxidant, and neuroprotective effects of polyphenols—polyphenols as an element of diet therapy in depressive disorders

A Winiarska-Mieczan, M Kwiecień… - International Journal of …, 2023 - mdpi.com
Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

Psychological stress and gut microbiota composition: A systematic review of human studies

L Ma, Y Yan, RJ Webb, Y Li, S Mehrabani, B Xin… - …, 2023 - karger.com
Introduction: The associations between psychological stress and gut microbiota composition
are not fully understood. This study investigated associations between psychological stress …

Toward understanding links between the microbiome and neurotransmitters

JB Lynch, EY Hsiao - Annals of the New York Academy of …, 2023 - Wiley Online Library
The gut microbiota modulates neurobiological activity in various animal lineages. This is
often proposed to occur through interactions with neurotransmitters and other …

Pick fecal microbiota transplantation to enhance therapy for major depressive disorder

Y Meng, J Sun, G Zhang - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
In recent years, fecal microbiota transplantation (FMT) has emerged as a promising therapy
for major depressive disorder (MDD). The goal of the operation is to restore a healthy gut …

Existing and future strategies to manipulate the gut microbiota with diet as a potential adjuvant treatment for psychiatric disorders

FC Ross, DE Mayer, A Gupta, CIR Gill, D Del Rio… - Biological …, 2024 - Elsevier
Nutrition and diet quality play key roles in preventing and slowing cognitive decline and
have been linked to multiple brain disorders. This review compiles available evidence from …

Gut microbiota signature in children with autism spectrum disorder who suffered from chronic gastrointestinal symptoms

H Wang, S Liu, L Xie, J Wang - BMC pediatrics, 2023 - Springer
Background Children diagnosed with autism spectrum disorder (ASD) frequently suffer from
persistent gastrointestinal symptoms, such as constipation and diarrhea. Various studies …

Altered gut bacterial–fungal interkingdom networks in children and adolescents with depression

S Hao, Z Zhang, Y Zhou, X Zhang, W Sun… - Journal of Affective …, 2023 - Elsevier
Background Most studies of the gut–brain axis have focused on bacteria; little is known
about commensal fungi. Children and adolescents with depression were reported to have …