[HTML][HTML] Predictors and management of relapse to Axicabtagene Ciloleucel in patients with aggressive B-cell lymphoma

JV Forero-Forero, PA Lengerke-Diaz… - … /Oncology and Stem Cell …, 2021 - Elsevier
Objective/background Despite the success of chimeric antigen receptor (CAR) T-cell therapy
in patients with aggressive non-Hodgkin lymphoma (aNHL), some patients still fail treatment …

Collection efficiency and safety of large‐volume leukapheresis for the manufacturing of tisagenlecleucel

W Kitamura, T Urata, K Fujii, T Fukumi, K Ikeuchi… - …, 2024 - Wiley Online Library
Background In patients with relapsed or refractory B cell acute lymphoblastic leukemia or B
cell non‐Hodgkin lymphoma (r/r B‐ALL/B‐NHL) with low CD3+ cells in the peripheral blood …

Persistent Cytopenia After CD19 CAR T Therapy in Relapsed/Refractory DLBCL Patients Could Be a Predictor of Efficacy and Side Effects

J Li, J Mu, J Wang, X Li, Q Li, Y Jiang… - Cell …, 2024 - journals.sagepub.com
Hematological toxicity is a severe adverse event (AE) in anti-CD19 chimeric antigen
receptor (CAR) T cell therapy for relapsed/refractory (R/R) diffuse large B-cell lymphoma …

Clinical strategies for enhancing the efficacy of CAR T-cell therapy for hematological malignancies

Q Liu, Z Liu, R Wan, W Huang - Cancers, 2022 - mdpi.com
Simple Summary Cellular immunotherapy has achieved great progress in the treatment of
hematological malignancies, and cell therapy may become the main force in the treatment of …

Current challenges and therapeutic advances of CAR-T cell therapy for solid tumors

T Chen, M Wang, Y Chen, Y Liu - Cancer Cell International, 2024 - Springer
The application of chimeric antigen receptor (CAR) T cells in the management of
hematological malignancies has emerged as a noteworthy therapeutic breakthrough …

血液肿瘤CAR-T 细胞治疗后血细胞减少的研究进展

曹钦婷, 冯茹 - 临床血液学杂志, 2024 - lcxy.whuhzzs.com
嵌合抗原受体(CAR) T 细胞在血液肿瘤治疗中的有效性得到广泛认可. CAR-T
相关不良反应有细胞因子释放综合征(cytokine release syndrome, CRS) …

Real-World Treatment Patterns After CD19-Directed CAR T Cell Therapy Among Patients with Diffuse Large B Cell Lymphoma

JJ Jalbert, N Wu, CI Chen, S Ambati, W Ge… - Advances in …, 2022 - Springer
Introduction CD19-directed chimeric antigen receptor T cells (CAR T) are approved for
treatment of adults with relapsed/refractory diffuse large B cell lymphoma (DLBCL) following …

Regulatory measures to improve the safety of CAR-T-cell treatment

P Berg, S Schönefeld, G Ruppert-Seipp… - Transfusion Medicine …, 2023 - karger.com
Introduction: Regulatory activities aim to facilitate the safe use of novel therapeutics such as
genetically engineered chimeric antigen receptor (CAR)-T cells. Toxicities associated with …

[HTML][HTML] Impact of SCHOLAR-1 Criteria on Chimeric Antigen Receptor T Cell Therapy Efficacy in Aggressive B Lymphoma: A Real-World GELTAMO/GETH Study

M Bastos-Oreiro, A Gutierrez, G Iacoboni… - … and cellular therapy, 2023 - Elsevier
In the pre-chimeric antigen receptor T cell (CAR-T) therapy era, the SCHOLAR-1 study
identified a group of patients with refractory aggressive B cell lymphoma (ABCL) with …

Gestión farmacoterapéutica de los medicamentos de terapias avanzadas

JL Poveda-Andrés, MJ Ruiz-Caldes… - Farmacia …, 2022 - SciELO Espana
Los medicamentos de terapia avanzada han emergido en los últimos años como nuevas
estrategias farmacoterapéuticas. En este contexto, los servicios de farmacia hospitalaria nos …